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Chemical Structure| 409086-68-6 Chemical Structure| 409086-68-6

Structure of YM-1
CAS No.: 409086-68-6

Chemical Structure| 409086-68-6

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YM-1 is an analog of MKT-077 with oral bioactivity that can stabilize Hsp70 inhibition. YM-1 induces cell death in HeLa cells while upregulating p53 and p21 protein levels, making it suitable for cancer research related to Hsp70.

4.5 *For Research Use Only! Not for Human Use. We Do Not Sell to Patients.

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Product Details of YM-1

CAS No. :409086-68-6
Formula : C20H20ClN3OS2
M.W : 417.98
SMILES Code : C[N+]1=CC=CC=C1C=C(N(CC)C2=O)SC2=C3SC4=CC=CC=C4N3C.[Cl-]
English Name :2-((3-Ethyl-5-(3-methylbenzo[d]thiazol-2(3H)-ylidene)-4-oxothiazolidin-2-ylidene)methyl)-1-methylpyridin-1-ium chloride
MDL No. :MFCD28009511

Safety of YM-1

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DNA

Isoform Comparison

Biological Activity

Description
YM-1, a stable, soluble analog of MKT-077, functions as an orally active inhibitor of Hsp70. It triggers cell death in HeLa cells and significantly increases the levels of p53 and p21 proteins, indicating its potential in modulating cell cycle and apoptosis pathways[1][2].

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1 mM

5 mM

10 mM

2.39mL

0.48mL

0.24mL

11.96mL

2.39mL

1.20mL

23.92mL

4.78mL

2.39mL

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