Home Chemistry Heterocyclic Building Blocks Pyrrolidines 2-((3-Phenylpropyl)Amino)-1-(Pyrrolidin-1-Yl)Ethan-1-One
Acylation Reaction: It can undergo acylation reactions with acyl chlorides or anhydrides to form amides. For example, you can react it with acetyl chloride to obtain the corresponding N-acetyl derivative.
Reduction: The ketone group can be reduced to an alcohol using reducing agents like sodium borohydride or lithium aluminum hydride.
Amination: The compound can undergo reductive amination reactions, where the ketone is converted to an amine. This can be achieved using various reagents such as primary or secondary amines and reducing agents like sodium cyanoborohydride.
Alkylation: The compound can undergo alkylation reactions. For instance, it can react with alkyl halides in the presence of a base to form N-alkylated derivatives.
Ring-Opening Reactions: The pyrrolidine ring can be opened under certain conditions. For example, treatment with strong acids can lead to ring-opening reactions, producing different products.
Nucleophilic Addition: The carbonyl group can undergo nucleophilic addition reactions with various nucleophiles, such as Grignard reagents, to form different adducts.
Oxidation: The compound can be oxidized to convert the amine group to an amide, or the alcohol group (if present) to a ketone or aldehyde.
Halogenation: If there are suitable reaction conditions, the compound can undergo halogenation reactions, adding halogen atoms to the molecule.
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