Home Chemistry Heterocyclic Building Blocks Indazoles Methyl 1H-Indazole-3-Carboxylate
Nucleophilic Substitution: The carboxylate group can undergo nucleophilic substitution reactions, such as ester hydrolysis or substitution with nucleophiles like amines or thiols.
Acid-Catalyzed Ester Hydrolysis: The ester linkage can undergo hydrolysis under acidic conditions to form the corresponding carboxylic acid and alcohol.
Reduction: The carbonyl group can be reduced to the corresponding alcohol using reducing agents such as lithium aluminum hydride or sodium borohydride.
Nucleophilic Addition: The indazole ring can undergo nucleophilic addition reactions with electrophiles, such as Michael additions or reactions with alkylating agents.
Ring-Closure Reactions: Methyl 1H-indazole-3-carboxylate can undergo ring-closure reactions to form cyclic compounds under suitable conditions.
Oxidation: The methyl group or other functional groups can be oxidized to form corresponding carbonyl compounds or carboxylic acids under appropriate conditions.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
Substitution Reactions: The indazole ring can undergo substitution reactions, such as nucleophilic aromatic substitution or electrophilic aromatic substitution.
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Methyl 4-methyl-1H-indazole-3-carboxylate
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Methyl 6-bromo-4-fluoro-1H-indazole-3-carboxylate
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Methyl 4-chloro-1H-indazole-3-carboxylate
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Methyl 4-bromo-1H-indazole-3-carboxylate
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Methyl 7-fluoro-1H-indazole-3-carboxylate
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Methyl 7-bromo-1H-indazole-3-carboxylate
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Methyl 6-methoxy-1H-indazole-3-carboxylate
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Methyl 6-fluoro-1H-indazole-3-carboxylate
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Methyl 6-methyl-1H-indazole-3-carboxylate
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Methyl 6-(trifluoromethyl)-1H-indazole-3-carboxylate
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Methyl 6-bromo-1H-indazole-3-carboxylate
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Methyl 6-nitro-1H-indazole-3-carboxylate
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Methyl 5-methoxy-1H-indazole-3-carboxylate
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Methyl 5-bromo-1H-indazole-3-carboxylate
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