Home Chemistry Organic Building Blocks Fluorinated Building Blocks (2-Fluorophenyl)Boronic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—B(OH)2).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Acid-Catalyzed Rearrangements: Phenylboronic acid can participate in acid-catalyzed rearrangement reactions, leading to the formation of different isomers or products.
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(2-Fluoro-3-methoxy-5-(methoxycarbonyl)phenyl)boronic acid
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(2,6-Difluoro-3-propoxyphenyl)boronic acid
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(2,4-Difluoro-3-propoxyphenyl)boronic acid
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(2-Fluoro-3-isobutoxyphenyl)boronic acid
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2,6-Difluoro-3-methylphenylboronic acid
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(2-Fluoro-6-methoxy-3-methylphenyl)boronic acid
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