Home Chemistry Organic Building Blocks Fluorinated Building Blocks (2-Fluorophenyl)Boronic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—B(OH)2).
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Acid-Catalyzed Rearrangements: Phenylboronic acid can participate in acid-catalyzed rearrangement reactions, leading to the formation of different isomers or products.
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(2,6-Difluoro-3-propoxyphenyl)boronic acid
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(2,4-Difluoro-3-propoxyphenyl)boronic acid
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(2-Fluoro-3-isobutoxyphenyl)boronic acid
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(4-Chloro-2-fluoro-3-methoxyphenyl)boronic acid
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(4-(tert-Butoxycarbonyl)-5-chloro-2-fluorophenyl)boronic acid
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6-Bromo-3-chloro-2-fluorophenylboronic acid
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(3-Bromo-6-fluoro-2-methoxyphenyl)boronic acid
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(2-Bromo-6-fluoro-3-methylphenyl)boronic acid
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(5-((tert-Butyldimethylsilyl)oxy)-2-fluorophenyl)boronic acid
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2-Chloro-6-fluoro-3-methylphenylboronic acid
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2-Fluoro-3-(trifluoromethyl)phenylboronic acid
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2-Fluoro-4-(trifluoromethyl)phenylboronic acid
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(3-Bromo-2-chloro-6-fluorophenyl)boronic acid
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(2,4-Difluoro-3-methoxyphenyl)boronic acid
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