Home Chemistry Organic Building Blocks Fluorinated Building Blocks (2-Fluorophenyl)Methanamine
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH2NH2).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Mannich Reaction: Phenylmethanamine can undergo Mannich reactions, where it reacts with formaldehyde and a secondary 【amine|https://www.ambeed.com/amines.html】 to form β-amino carbonyl compounds.
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3-(Aminomethyl)-2-fluorophenol hydrobromide
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(4-Bromo-2,6-difluorophenyl)methanamine
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(Perfluoro-1,4-phenylene)dimethanamine acetate
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(3,6-Dichloro-2-fluorophenyl)methanamine hydrochloride
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(4-Bromo-2,6-difluorophenyl)methanamine hydrochloride
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(3-Bromo-2-fluorophenyl)methanamine HCl
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2-(Difluoromethoxy)-6-fluorobenzylamine hydrochloride
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(2-Fluoro-6-methoxyphenyl)methanamine hydrochloride
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(4-Chloro-2-fluorophenyl)methanamine hydrochloride
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(4-Bromo-2-fluorophenyl)methanamine hydrochloride
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