Home Chemistry Heterocyclic Building Blocks Piperidines (9H-Fluoren-9-Yl)Methyl Piperidine-1-Carboxylate
Amine Reactions: The piperidine ring contains a secondary amine, which can participate in various reactions such as acylation, alkylation, or reductive amination.
Grignard Reaction: The compound can react with a Grignard reagent, typically in the presence of a catalyst like magnesium, to form a tertiary alcohol.
Substitution: The benzyl groups can undergo nucleophilic aromatic substitution reactions (SNAr), where the benzyl group can be substituted with various nucleophiles under appropriate conditions.
Esterification: The carboxylic acid functionality can be esterified using a variety of reagents such as acyl chlorides or anhydrides to form different esters.
Decarboxylation: Under certain conditions, the carboxylic acid group can undergo decarboxylation to form the corresponding alkane.
Amide Formation: The carboxylic acid can react with amines to form amides. This reaction can be catalyzed by various activating agents.
Nitrile Formation: The carboxylic acid can be converted into a nitrile using appropriate reagents like thionyl chloride (SOCl2).
Ester Hydrolysis: The benzyl ester groups can also undergo hydrolysis in the presence of acid or base, leading to the formation of benzyl alcohols and the corresponding carboxylic acids.
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(9H-Fluoren-9-yl)methyl 3-(aminomethyl)piperidine-1-carboxylate hydrochloride
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(9H-Fluoren-9-yl)methyl 4-aminopiperidine-1-carboxylate hydrochloride
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(9H-Fluoren-9-yl)methyl 3-aminopiperidine-1-carboxylate hydrochloride
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