Home Chemistry Heterocyclic Building Blocks Aliphatic Heterocycles 1,4-Diazepan-2-One
Hydrolysis: 1,4-diazepan-2-one can undergo hydrolysis in the presence of an acid or base to yield the corresponding carboxylic acid and amine. For example, in acidic conditions, it can be converted to a carboxylic acid and a secondary amine.
Ring-Opening Reactions: The seven-membered ring can be opened under certain conditions, such as heating with strong bases or nucleophiles, to form various products. The resulting product will depend on the nature of the nucleophile used.
Nucleophilic Substitution: The ketone functional group in 1,4-diazepan-2-one can undergo nucleophilic substitution reactions with nucleophiles to form substituted products.
Esterification: 1,4-diazepan-2-one can undergo esterification reactions with acyl chlorides or anhydrides to form esters.
Reductive Reactions: It can be subjected to reduction reactions to convert the ketone group to a corresponding alcohol group. This can be achieved using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Oxidative Reactions: It can also undergo oxidation reactions to convert the ketone group to a corresponding carboxylic acid or other oxidized functional groups.
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tert-Butyl 5-methyl-3-oxo-1,4-diazepane-1-carboxylate
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