Home Chemistry Heterocyclic Building Blocks Benzimidazoles 1-Benzyl-1H-Benzo[D]Imidazole
Acylation: 1-Benzyl-1H-benzo[d]imidazole can undergo acylation reactions with acyl chlorides or anhydrides to form benzylbenzo[d]imidazolyl ketones or esters.
Alkylation: It can be alkylated with alkyl halides or alkylating agents under suitable conditions to introduce alkyl groups onto the benzimidazole ring.
Debenzylation: The benzyl group can be removed from the molecule under acidic or reducing conditions to form the parent benzimidazole compound.
Substitution reactions: Depending on the reaction conditions, substitution reactions can occur at various positions of the benzimidazole ring. For example, nucleophilic substitution reactions can occur at the C-2 position.
Condensation reactions: It can participate in condensation reactions to form larger molecules, especially when other functional groups are present.
Metal-catalyzed reactions: Transition metal catalysts can facilitate various reactions, including cross-coupling reactions, that can lead to the formation of more complex molecules.
Lewis acid-catalyzed reactions: Lewis acids can catalyze reactions involving the benzimidazole ring, such as Friedel-Crafts acylation or alkylation reactions.
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(1-Benzyl-1H-benzo[d]imidazol-2-yl)methanol
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(1-Benzyl-1H-benzo[d]imidazol-2-yl)methanamine dihydrochloride
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