Chemistry Heterocyclic Building Blocks Pyrazoles 1-Cyclopentyl-1H-Pyrazole

1-Cyclopentyl-1H-Pyrazole

Substitution Reactions: Like many aromatic compounds, 1-cyclopentyl-1H-pyrazole can undergo electrophilic aromatic substitution reactions. For example, it can react with strong electrophiles (e.g., acyl chlorides, nitration reagents) to substitute hydrogen atoms on the pyrazole ring with various functional groups. Nucleophilic Substitution: If suitable leaving groups are present on the cyclopentyl or pyrazole ring, nucleophilic substitution reactions can occur. For instance, the compound can react with nucleophiles, such as amines or alkoxides, to replace a leaving group on the molecule. Oxidation: 1-Cyclopentyl-1H-pyrazole can undergo oxidation reactions. Oxidizing agents can convert it into compounds with more oxygen atoms, depending on the conditions. Oxidation could lead to the formation of pyrazole N-oxides or other oxygen-containing functional groups. Reduction: The compound can also be reduced under suitable conditions, converting functional groups to more reduced forms. For example, reduction with strong reducing agents can lead to the formation of the corresponding amines or even fully reduced derivatives. Acylation: 1-Cyclopentyl-1H-pyrazole can undergo acylation reactions, where acyl groups are added to the molecule. This is often achieved by reacting it with acyl halides or anhydrides in the presence of a base. Alkylation: Alkylation reactions can be carried out by reacting 1-cyclopentyl-1H-pyrazole with alkylating agents in the presence of a base. This can result in the introduction of alkyl groups onto the pyrazole ring. Condensation Reactions: Depending on the functional groups present, 1-cyclopentyl-1H-pyrazole can participate in condensation reactions to form larger molecules. For instance, it can undergo a Mannich reaction when treated with formaldehyde and a primary or secondary amine. Metalation: The pyrazole ring can serve as a ligand for various metal ions. Reactions with metal ions can lead to the formation of coordination complexes, which may have unique properties and reactivities.

Further Reading:

Framework+−

(1-Methyl-1H-Pyrazol-3-Yl)Methanol (1-Phenyl-1H-Pyrazol-4-Yl)Boronic Acid 1,3-Dimethyl-1H-Pyrazole 1,3-Diphenyl-1H-Pyrazole 1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazole 1,5-Diphenyl-1H-Pyrazole 1-(2-Chlorophenyl)-1H-Pyrazole 1-(3-Chlorophenyl)-1H-Pyrazole 1-(4-Methoxybenzyl)-1H-Pyrazole 1-(Azetidin-3-Yl)-1H-Pyrazole 1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazole 1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazole 1-Benzyl-1H-Pyrazolo[3,4-B]Pyridine 1-Benzyl-4-Bromo-1H-Pyrazole 1-Benzyl-4-Iodo-1H-Pyrazole 1-Cyclopentyl-1H-Pyrazole 1-Cyclopropyl-1H-Pyrazole 1-Methyl-1H-Pyrazol-3-Amine 1-Methyl-3-Phenyl-1H-Pyrazole 1-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole 1-Methyl-5-Phenyl-1H-Pyrazole 1-Phenyl-1H-Pyrazol-3-Amine 1-Phenyl-1H-Pyrazol-3-Ol 1-Phenyl-1H-Pyrazol-5-Amine 1-Phenyl-1H-Pyrazole-3-Carboxylic Acid 1-Phenyl-1H-Pyrazole-4-Carbaldehyde 1-Phenyl-1H-Pyrazole-4-Carbonitrile 1-Phenyl-1H-Pyrazole-4-Carboxylic Acid 1-Phenyl-1H-Pyrazole-5-Carboxylic Acid 1-Phenyl-3-(Trifluoromethyl)-1H-Pyrazole 1-Trityl-1H-Pyrazole 1H-Pyrazol-4-Amine 1H-Pyrazol-4-Ol 1H-Pyrazol-5-Amine 1H-Pyrazole-4-Carbaldehyde 1H-Pyrazole-4-Carbonitrile 1H-Pyrazole-4-Carboxylic Acid 1H-Pyrazole-4-Sulfonyl Chloride 1H-Pyrazole-5-Carboxamide 1H-Pyrazole-5-Carboxylic Acid 1H-Pyrazolo[3,4-B]Pyrazine 1H-Pyrazolo[3,4-B]Pyridin-5-Amine 1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine 1H-Pyrazolo[4,3-D]Pyrimidine 2,3-Dihydropyrazolo[5,1-B]Oxazole 2,4-Dihydro-3H-Pyrazol-3-One 2,6-Di(1H-Pyrazol-1-Yl)Pyridine 2-(1H-Pyrazol-1-Yl)Pyridine 2-(1H-Pyrazol-1-Yl)Pyrimidine 2-(1H-Pyrazol-3-Yl)Pyridine 2-Phenyl-2,4-Dihydro-3H-Pyrazol-3-One 3-(Tert-Butyl)-1-Phenyl-1H-Pyrazole 3-Bromo-1-Methyl-1H-Pyrazole 3-Bromopyrazolo[1,5-A]Pyridine 3-Bromopyrazolo[1,5-A]Pyrimidine 3-Chloro-1-Methyl-1H-Pyrazole 3-Cyclopropyl-1H-Pyrazole 3-Iodo-1-Methyl-1H-Pyrazole 3-Iodo-1H-Pyrazolo[3,4-B]Pyridine 3-Methyl-1-Phenyl-1H-Pyrazole 3-Phenyl-1H-Pyrazol-5-Amine 4,5,6,7-Tetrahydro-1H-Pyrazolo[3,4-C]Pyridine 4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridine 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine 4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyridine 4-(1H-Pyrazol-1-Yl)Benzoic Acid 4-(1H-Pyrazol-1-Yl)Piperidine 4-Bromo-1-Methyl-1H-Pyrazole 4-Bromo-1-Phenyl-1H-Pyrazole 4-Bromo-1H-Pyrazolo[3,4-B]Pyridine 4-Bromopyrazolo[1,5-A]Pyridine 4-Chloro-1H-Pyrazole 4-Chloro-1H-Pyrazolo[3,4-B]Pyridine 4-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine 4-Iodo-1H-Pyrazole 4-Methyl-1-Phenyl-1H-Pyrazole 4-Methyl-1H-Pyrazole 4-Nitro-1H-Pyrazole 4-Phenyl-1H-Pyrazole 5,6-Dihydro-4H-Pyrrolo[1,2-B]Pyrazole 5-(Difluoromethyl)-1H-Pyrazole 5-Bromo-1H-Pyrazole 5-Bromo-1H-Pyrazolo[3,4-B]Pyridine 5-Bromo-1H-Pyrazolo[3,4-C]Pyridine 5-Chloro-1H-Pyrazole 5-Chloro-1H-Pyrazolo[3,4-B]Pyridine 5-Chloropyrazolo[1,5-A]Pyrimidine 5-Cyclopropyl-1H-Pyrazole 5-Iodo-1H-Pyrazole 5-Nitro-1H-Pyrazole 5-Nitro-1H-Pyrazolo[3,4-B]Pyridine 5-Phenyl-1H-Pyrazole-3-Carboxylic Acid 6,7-Dihydro-5H-Pyrazolo[5,1-B][1,3]Oxazine 6-Bromopyrazolo[1,5-A]Pyridine 6-Bromopyrazolo[1,5-A]Pyrimidine 6-Chloro-1H-Pyrazolo[3,4-D]Pyrimidine 7-Chloropyrazolo[1,5-A]Pyrimidine Ethyl 1-Phenyl-1H-Pyrazole-3-Carboxylate Ethyl 1-Phenyl-1H-Pyrazole-4-Carboxylate Ethyl 1H-Pyrazole-4-Carboxylate Ethyl Pyrazolo[1,5-A]Pyridine-3-Carboxylate Ethyl Pyrazolo[1,5-A]Pyrimidine-3-Carboxylate Methyl 1H-Pyrazole-4-Carboxylate Methyl 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate Methyl Pyrazolo[1,5-A]Pyridine-3-Carboxylate Pyrazolo[1,5-A]Pyrazine Pyrazolo[1,5-A]Pyridine-2-Carboxylic Acid Pyrazolo[1,5-A]Pyridine-3-Carboxylic Acid Pyrazolo[1,5-A]Pyrimidine-3-Carboxylic Acid Tert-Butyl 1H-Pyrazolo[3,4-B]Pyridine-1-Carboxylate Tert-Butyl 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole-1-Carboxylate

By Key Group+−

Amino-Pyrazole-Carboxylate Amino-Pyrazolopyridine Aminopyrazolo Benzylpyrazol-Amide Bipyrazole Bromo-Methyl-Pyrazole Bromo-Pyrazol-Amide Bromo-Pyrazole-Carboxylate Bromo-Pyrazolopyridine Bromo-Pyrazolopyrimidine Bromo-Trifluoromethyl-Pyrazole Bromopyrazolo Chloro-Methyl-Pyrazole Chloro-Pyrazolamide Chloro-Pyrazole Chloro-Pyrazole-Carboxylate Chloro-Pyrazolopyridine Chloro-Pyrazolopyrimidine Chloropyrazolo Dichloropyrazolo Difluoromethyl-Pyrazole Difluoromethyl-Pyrazole-Carboxylate Dihydropyrazolo Dimethyl-Pyrazol-Amide Dimethyl-Pyrazole-Carboxylate Dimethyl-Pyrazole-Carboxylic Acid Dimethylpyrazole Dimethylpyrazolo Dioxaborolan-Pyrazole Ethyl-Pyrazol-Amide Ethylpyrazole Fluoropyrazolo Hydroxy-Pyrazole Hydroxy-Pyrazolopyrimidine Hydroxypyrazolo Iodo-Methyl-Pyrazole Iodo-Pyrazole-Carboxylate Iodopyrazolo Isopropyl-Pyrazol-Amide Methoxy-Pyrazolo-Pyridine Methoxypyrazolo Methy-Pyrazolooxazine Methyl-Hydrox-Ypyrazole Methyl-Nitro-Pyrazole Methyl-Pyrazol-One Methyl-Pyrazole-Carboxylic Acid Methyl-Pyrazole-Carboxylic-Acid Methyl-Pyrazolone Methyl-Pyrazolopyridine Methylpyrazole Methylpyrazolo Nitro-Pyrazole-Carboxylate Phenyl-Pyrazol-Amide Phenyl-Pyrazole-Carboxylate Phenyl-Pyrazolidine Phenylpyrazole Pyrazo-Morpholine Pyrazol-Amine Pyrazol-Boronic Acid Pyrazol-Methanol Pyrazol-One Pyrazol-Piperazine Pyrazol-Pyridine Pyrazole-Carbonitrile Pyrazole-Carboxylate Pyrazole-Carboxylic Acid Pyrazole-Ethanol Pyrazole-Hydrochloride Pyrazole-Methamine Pyrazole-Phenyl-Boronic-Acid Pyrazole-Piperidine Pyrazolo-Pyrimidine Pyrazolooxazine Pyrazolopyrazine Pyrazolopyridin-Ol Pyrazolopyridin-One Pyrazolopyridine Pyrazolopyridine-Carbonitrile Pyrazolopyridine-Carboxylate Pyrazolopyridine-Carboxylic Acid Pyrazolopyridine-Carboxylic-Acid Pyrazolopyridine-Methanol Pyrazolopyrimid-One Pyrazolopyrimidine Pyrazolotriazine Pyridine-Pyrazole Pyrimidine-Pyrazole Pyrrolopyrazole Tetrahydropyran-Pyrazole Tetrahydropyranopyrazole Tetrahydropyrazolo Trifluoromethyl-Phenyl-Pyrazol Trifluoromethyl-Pyrazol-Amide Trifluoromethyl-Pyrazole Trifluoromethyl-Pyrazolone

By Parent Nucleus+−

Aliphatic Heterocycles Aromatic Heterocycles Azetidines Furans Guanidines Imidazoles Indazoles Indoles Other Aliphatic Heterocycles Other Aromatic Heterocycles Oxetanes Piperazines Piperidines Pyrazines Pyridazines Pyridines Pyrimidines Pyrroles Pyrrolidines Quinolines Tetrahydrofurans Tetrahydropyrans Thiophenes

By Functional Group+−

Alcohols Aldehydes Aliphatic Chain Hydrocarbons Aliphatic Cyclic Hydrocarbons Alkenyls Alkyls Alkynyls Amides Amines Aryls Benzyl Bromides Benzyl Chlorides Bromides Carboxylic Acids Chiral Building Blocks Chlorides Difluoromethyls Esters Ethers Fluorinated Building Blocks Hydrazones Iodides Ketones Nitriles Nitroes Oximes Phenols Phosphoruses Sulfamides Sulfides Sulfonates Sulfonic Acids Sulfonyl Chlorides Trifluoromethyls Ureas

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    Typically In Stock
    Purity
    • Please Select
    • 99+%
    • 99%
    • 98+%
    • 98%
    • 97+%
    • 97%
    • 96+%
    • 96%
    • 95+%
    • 95%
    • 93%
    • 90+%
    • 90%
    Size
    • Please Select
    • 1mg
    • 2mg
    • 5mg
    • 10mg
    • 25mg
    • 50mg
    • 100mg
    • 250mg
    • 1g
    • 5g
    • 10g
    • 25g
    • 100g
    • 500g
    • 1000g
    • 1kg
    Clear Filters
    Ethyl 1-cyclopentyl-5-hydroxy-1H-pyrazole-4-carboxylate

    click to sign in and save

    A10034191547888-86-797%

    Ethyl 1-cyclopentyl-5-hydroxy-1H-pyrazole-4-carboxylate

    $37.00/250mg

    Detail
    3-Amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile

    click to sign in and save

    A223085122799-98-895%

    3-Amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile

    $25.00/100mg

    Detail
    4-Bromo-1-cyclopentyl-3-(trifluoromethyl)-1H-pyrazole

    click to sign in and save

    A1444451437794-36-995%

    4-Bromo-1-cyclopentyl-3-(trifluoromethyl)-1H-pyrazole

    $55.00/5g

    Detail
    (1-Cyclopentyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid

    click to sign in and save

    A1307622304634-13-595%

    (1-Cyclopentyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)boronic acid

    $375.00/1g

    Detail
    1-Cyclopentyl-1h-pyrazol-5-ol

    click to sign in and save

    A7967271566287-80-695%

    1-Cyclopentyl-1h-pyrazol-5-ol

    $91.00/250mg

    Detail
    1    page 1 of 1 Pages

    Inquiry