Home Chemistry Heterocyclic Building Blocks Azetidines 1-Phenylazetidine
Ring-opening reactions: Due to the high ring strain, 1-phenylazetidine can undergo ring-opening reactions, especially under the influence of heat or appropriate reagents. Ring opening can occur through nucleophilic attack at the aziridine carbon, leading to the formation of open-chain products.
Electrophilic additions: The phenyl group attached to the azetidine ring can undergo electrophilic aromatic substitution reactions. For example, it can react with electrophiles like acyl chlorides, nitration reagents, or Friedel-Crafts acylation agents.
Nucleophilic substitutions: The azetidine ring nitrogen can act as a nucleophile and participate in reactions with electrophiles. For instance, it can undergo alkylation or acylation reactions when treated with appropriate alkyl halides or acyl halides.
Reduction reactions: 1-Phenylazetidine can be reduced to form the corresponding amine using reducing agents like lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Oxidation reactions: It can be oxidized to various functional groups, depending on the reaction conditions. For example, oxidation with a mild oxidizing agent like potassium permanganate (KMnO4) can lead to the formation of a ketone or carboxylic acid.
Ring-closing reactions: 1-Phenylazetidine can participate in ring-closing reactions to form other cyclic compounds when treated with appropriate reagents or conditions.
Rearrangement reactions: Under certain conditions, rearrangement reactions can occur, leading to the formation of different isomeric compounds.
Framework+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
click to sign in and save
1-(4-Formylphenyl)azetidine-3-carboxylic acid
click to sign in and save
1-(4-Chlorophenyl)azetidine-3-carboxylic acid
Deals
click to sign in and save
4-(3-Hydroxyazetidin-1-yl)benzoic acid
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :