Home Chemistry Heterocyclic Building Blocks Azetidines 2,7-Diazaspiro[3.5]Nonane
Nucleophilic Substitution Reactions: The nitrogen atoms in the diazaspiro[3.5]nonane can act as nucleophiles and undergo substitution reactions with electrophiles. For example, they can react with alkyl halides to form N-alkylated derivatives.
Acylation: The compound can react with acyl chlorides or anhydrides to form amides. This reaction typically involves the attack of the amine nitrogen on the carbonyl carbon of the acyl group.
Ring-Opening Reactions: The spiro[3.5]nonane ring can potentially undergo ring-opening reactions under certain conditions. For example, it may react with strong acids or nucleophiles at specific positions, leading to the cleavage of the ring and the formation of open-chain compounds.
Reduction: Like many amines, 2,7-diazaspiro[3.5]nonane can be reduced using reducing agents such as lithium aluminum hydride (LiAlH4) to form the corresponding saturated amine or even a secondary amine, depending on the reaction conditions.
Alkylation: The amine groups in the compound can be alkylated using alkyl halides or other alkylating agents to introduce alkyl substituents onto the nitrogen atoms.
Oxidation: It may undergo oxidation reactions, such as with strong oxidizing agents, to form compounds with oxidized nitrogen centers.
Cyclization: Depending on the reaction conditions and reagents, it can potentially undergo intramolecular cyclization reactions to form different cyclic structures or isomers.
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tert-Butyl 2,7-diazaspiro[3.5]nonane-2-carboxylate HCl
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2-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride
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tert-Butyl 7-(prop-2-yn-1-yl)-2,7-diazaspiro[3.5]nonane-2-carboxylate
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2-(tert-Butoxycarbonyl)-2,7-diazaspiro[3.5]nonane
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tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate
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tert-butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate HCl
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7-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride
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