Home Chemistry Organic Building Blocks Chlorides 2-(2-Chlorophenyl)Pyrrolidine
Nucleophilic Substitution: The chlorine atom in the chlorophenyl group can undergo nucleophilic substitution reactions, where it can be replaced by a nucleophile. For example, it can react with a strong nucleophile like sodium hydroxide to form 2-(2-hydroxyphenyl)pyrrolidine.
Alkylation or Acylation: The pyrrolidine nitrogen atom can act as a nucleophile and react with alkyl halides or acyl halides to form alkylated or acylated derivatives of the compound.
Reductive Amination: 2-(2-chlorophenyl)pyrrolidine can be subjected to reductive amination reactions where the nitrogen atom can be converted to an amine by reacting with a suitable aldehyde or ketone in the presence of a reducing agent like sodium borohydride.
Oxidation: The compound can undergo oxidation reactions to convert the pyrrolidine nitrogen to a pyrrolidinone or other oxidized forms.
Grignard Reaction: The compound can react with a Grignard reagent, forming a new carbon-carbon bond, and leading to the addition of a new functional group to the molecule.
Ring-opening Reactions: Depending on the conditions and reagents, the pyrrolidine ring can undergo ring-opening reactions to form open-chain compounds.
Amide Formation: The compound can react with carboxylic acid derivatives (e.g., acyl chlorides) to form amides by amidation.
Reduction: The compound can undergo reduction reactions to convert functional groups to their reduced forms.
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(R)-2-(2-Chlorophenyl)pyrrolidine hydrochloride
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(R)-2-(2,3-Dichlorophenyl)pyrrolidine hydrochloride
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(R)-2-(2-Chloro-4-methylphenyl)pyrrolidine hydrochloride
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(R)-2-(2-Chloro-3-methylphenyl)pyrrolidine hydrochloride
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(R)-2-(2,5-Dichlorophenyl)pyrrolidine hydrochloride
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(R)-2-(2,6-Dichlorophenyl)pyrrolidine hydrochloride
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(R)-2-(2-Chloro-5-fluorophenyl)pyrrolidine hydrochloride
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(R)-2-(2-Chloro-4-fluorophenyl)pyrrolidine hydrochloride
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(R)-2-(2-Chloro-6-fluorophenyl)pyrrolidine hydrochloride
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(R)-2-(2-chloro-5-fluorophenyl)pyrrolidine
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2-(2,4-Dichlorophenyl)pyrrolidine hydrochloride
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2-(2,5-Dichlorophenyl)pyrrolidine hydrochloride
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