Home Chemistry Organic Building Blocks Fluorinated Building Blocks 2-(4-Fluorophenyl)Acetic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—CH2COOH).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Amide Formation: It can react with 【amines|https://www.ambeed.com/amines.html】 to form 【Amides|https://www.ambeed.com/amides.html】 in the presence of suitable activating agents or reagents. Reaction: 2-Phenylacetic acid + amine → Amide + Water
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2-(4,5-Difluoro-2-nitrophenyl)acetic acid
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4-Fluoro-2-(trifluoromethyl)phenylacetic acid
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2-(4-Fluoro-2-(trifluoromethoxy)phenyl)acetic acid
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4-Fluoro-3-(trifluoromethyl)phenylacetic acid
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