Home Chemistry Organic Building Blocks Carboxylic Acids 2-Chloro-6-Fluorobenzoic Acid
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Cl,—COOH,—F).
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
Esterification: Benzoic acid can undergo esterification reactions with 【alcohols|https://www.ambeed.com/alcohols.html】 in the presence of a catalyst, typically an acid catalyst like sulfuric acid. This reaction leads to the formation of benzoate 【esters|https://www.ambeed.com/esters.html】 and water.
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
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2-Chloro-6-fluoro-3-methoxybenzoic acid
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