Home Chemistry Heterocyclic Building Blocks Piperidines 3,3-Dimethylpiperidine
Nucleophilic Substitution: The nitrogen atom in the piperidine ring can act as a nucleophile and undergo substitution reactions with various electrophiles, such as alkyl halides or acyl chlorides, leading to the formation of substituted piperidines.
Alkylation: The nitrogen atom in the piperidine ring can be alkylated by reaction with alkyl halides or sulfonates.
Acylation: The nitrogen atom in the piperidine ring can undergo acylation reactions to form N-acyl derivatives.
Reduction: The imine group can be reduced to the corresponding amine using reducing agents such as sodium borohydride or hydrogen gas over a metal catalyst.
Ring-opening Reactions: The piperidine ring may undergo ring-opening reactions under certain conditions, leading to the formation of linear or branched compounds.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.Dehydration: Under appropriate conditions, dehydration reactions can occur to eliminate water and form unsaturated compounds.
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tert-Butyl 4-amino-3,3-dimethylpiperidine-1-carboxylate
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(R)-tert-Butyl 4-amino-3,3-dimethylpiperidine-1-carboxylate
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(S)-tert-Butyl 4-amino-3,3-dimethylpiperidine-1-carboxylate
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tert-Butyl 4-hydroxy-3,3-dimethylpiperidine-1-carboxylate
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