Home Chemistry Organic Building Blocks Chlorides 3-Chloro-2-Fluorobenzonitrile
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —Cl,—F,—C≡N).
Electrophilic Substitution Reactions: Chlorobenzene's electron-rich aromatic ring can undergo substitution reactions where a hydrogen atom is replaced by a chlorine atom. For instance, it can undergo nitration, sulfonation, and Friedel-Crafts alkylation/acylation reactions.
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
Cyanation and Cyanation Reactions: The cyano group in benzonitrile can serve as a nucleophile in various reactions, leading to the introduction of cyano groups onto other molecules.
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