Chemistry Organic Building Blocks Aryls 3-Styrylphenol

3-Styrylphenol

These compounds have the same murcko framework: 3-styrylphenol

Aromatic Substitution: The phenolic group can undergo electrophilic aromatic substitution reactions, where the aromatic ring reacts with electrophiles, such as acyl halides or anhydrides, leading to the formation of substituted phenolic compounds.
Oxidation: The phenolic group can be oxidized to form quinones under certain conditions. This can be achieved using oxidizing agents.
Michael Addition: The styryl group can participate in Michael addition reactions, where the double bond acts as a nucleophile and reacts with an electrophile. This is particularly relevant if there are suitable Michael acceptors present in the reaction.
Hydrogenation: The styryl group's double bond can undergo hydrogenation in the presence of a suitable catalyst, leading to the saturation of the double bond.
Esterification: The phenolic hydroxyl group can react with carboxylic acids or acid derivatives to form esters.
Etherification: The phenolic hydroxyl group can react with alkyl halides or alkyl sulfonates to form ethers.
Alkylation: Both the phenolic hydroxyl and styryl groups could potentially undergo alkylation reactions under appropriate conditions.
Cross-Coupling Reactions: The styryl group can participate in various cross-coupling reactions, such as Suzuki, Heck, or Stille couplings, to form biaryl compounds.
Condensation Reactions: The phenolic group can participate in condensation reactions, such as the Claisen-Schmidt condensation, with carbonyl compounds to form α,β-unsaturated ketones.

Further Reading:

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((2S,6S)-6-Phenoxytetrahydro-2H-Pyran-2-Yl)Methanol (2S,4S)-2-Phenoxytetrahydro-2H-Pyran-4-Yl Acetate (6-Phenoxytetrahydro-2H-Pyran-2-Yl)Methanol (8S,9S,14R)-1,2,6,7,8,9,10,11,12,13,14,15,16,17-Tetradecahydro-3H-Cyclopenta[A]Phenanthren-3-One (8S,9S,14R)-7,8,9,11,12,13,14,15,16,17-Decahydro-6H-Cyclopenta[A]Phenanthrene (9H-Fluoren-9-Yl)Methyl (2-(Tritylthio)Ethyl)Carbamate (9H-Fluoren-9-Yl)Methyl Cyclohexylcarbamate (Benzylsulfonyl)Benzene (Cyclopentyloxy)Benzene (E)-1-(2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One (E)-3-Styrylphenol 1,1-Dimethylcyclopropane 1,2-Bis(Diphenylphosphaneyl)Ethane 1,3,4,5-Tetrahydro-2H-Benzo[B]Azepin-2-One 1,3-Diphenylurea 1-(2-Hydroxyphenyl)-2-Phenylethan-1-One 1-(2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One 1-([1,1'-Biphenyl]-4-Yl)Ethan-1-One 1-(Naphthalen-2-Yl)Ethan-1-One 1-Benzyl-4-Chlorobenzene 1-Benzyl-4-Fluorobenzene 1-Bromonaphthalene 1-Chloronaphthalene 1-Fluoronaphthalene 1-Methoxynaphthalene 1-Methyl-4-(Phenylethynyl)Benzene 1-Methylnaphthalene 1-Naphthaldehyde 1-Naphthoic Acid 1-Nitronaphthalene 10H-Phenothiazine 2,2',3,3',5,5',6,6'-Octafluoro-1,1'-Biphenyl 2,5-Diphenylthiophene 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenol 2-(Trifluoromethyl)-1,1'-Biphenyl 2-Benzylaniline 2-Bromo-1,1'-Biphenyl 2-Bromonaphthalene 2-Chloro-1,1'-Biphenyl 2-Chloronaphthalene 2-Ethoxynaphthalene 2-Fluorocyclopropane-1-Carboxylic Acid 2-Hydroxycyclohexa-2,5-Diene-1,4-Dione 2-Iodonaphthalene 2-Methoxy-1,1'-Biphenyl 2-Methoxynaphthalene 2-Methoxytetrahydro-2H-Pyran 2-Methyl-1,1'-Biphenyl 2-Methylnaphthalene 2-Naphthaldehyde 2-Naphthoic Acid 2-Naphthonitrile 2-Nitronaphthalene 2-Phenoxytetrahydro-2H-Pyran-4-Yl Acetate 2-Phenylnaphthalene 3,3'-Diphenyl-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthalene 3,3-Diphenyl-3H-Benzo[C][1,2]Oxathiole 1,1-Dioxide 3-Bromo-1,1'-Biphenyl 3-Chloro-1,1'-Biphenyl 3-Fluoro-1,1'-Biphenyl 3-Methyl-1,1'-Biphenyl 3-Methyl-1,1':4',1''-Terphenyl 3-Phenethylphenol 3-Phenyl-1,2,4,5-Tetrazine 3-Styrylphenol 4-(Bromomethyl)-1,1'-Biphenyl 4-(Phenyldiazenyl)Benzoic Acid 4-(Phenylsulfonyl)Morpholine 4-(Tert-Butyl)-1,1'-Biphenyl 4-Cyclohexylphenol 4-Iodo-1,1'-Biphenyl 4-Methoxy-1,1'-Biphenyl 9H-Xanthene [1,1'-Biphenyl]-2-Amine [1,1'-Biphenyl]-2-Carbonitrile [1,1'-Biphenyl]-2-Carboxylic Acid [1,1'-Biphenyl]-2-Ol [1,1'-Biphenyl]-3-Amine [1,1'-Biphenyl]-3-Carbaldehyde [1,1'-Biphenyl]-3-Carboxylic Acid [1,1'-Biphenyl]-3-Ol [1,1'-Biphenyl]-4-Carbaldehyde [1,1'-Biphenyl]-4-Carbonitrile [1,1'-Biphenyl]-4-Ol [1,1'-Biphenyl]-4-Ylboronic Acid Benzyltriphenylphosphonium Cyclopentylbenzene Cyclopropanecarboxylic Acid Cyclopropyl(Phenyl)Methanamine Cyclopropyl(Phenyl)Methanone Diphenyl Phosphonate Diphenylphosphane Diphenylphosphine Oxide Ethane-1,1-Diyldibenzene Ethene-1,1,2-Triyltribenzene Ethyl Cyclopropanecarboxylate Methyl 1-Naphthoate Methyl 2-Naphthoate Methyl [1,1'-Biphenyl]-4-Carboxylate Methyl Cyclopropanecarboxylate N,1-Diphenylmethanimine N,N-Dimethylnaphthalen-1-Amine N-((5R,6R)-7-Oxo-4-Thia-1-Azabicyclo[3.2.0]Heptan-6-Yl)-2-Phenylacetamide N-Benzylbenzamide N-Benzylbenzenesulfonamide N-Cyclopropylbenzamide N-Cyclopropylbenzenesulfonamide N-Phenethylbenzamide N-Phenyl-2-Naphthamide Naphthalen-1-Ol Naphthalen-1-Ylboronic Acid Naphthalen-1-Ylmethanol Naphthalen-2-Amine Naphthalen-2-Ol Naphthalen-2-Ylboronic Acid Naphthalene-1,4-Diol Naphthalene-2-Sulfonic Acid Propane-2,2-Diyldibenzene Tert-Butyl Cyclopropylcarbamate Tetrahydro-2H-Pyran-2-Ol Tetrahydro-2H-Pyran-2-Yl Acetate Tetraphenylmethane Triphenylene Vinylcyclopropane

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