Home Chemistry Heterocyclic Building Blocks Indoles 5-(Benzyloxy)-1H-Indole
Nucleophilic Substitution: The benzyloxy group can undergo nucleophilic substitution reactions, such as with strong nucleophiles like sodium or potassium hydroxide to replace the benzyloxy group with hydroxide or other nucleophiles.
Aromatic Substitution: The indole ring can undergo electrophilic aromatic substitution reactions, such as Friedel-Crafts acylation or alkylation, which can introduce various substituents onto the aromatic ring.
Debenzylation: The benzyloxy group can be removed using reagents like hydrogen and palladium, or strong acids like hydrogen bromide, to yield the parent indole.
Oxidation: The compound can be subjected to oxidation reactions, leading to the formation of various products depending on the oxidizing agent used.
Reduction: Reduction reactions can be used to reduce the indole ring or other functional groups within the molecule.
Addition Reactions: Depending on the reaction conditions and reagents, addition reactions, such as addition of a nucleophile to a double bond or addition to the indole ring, can occur.
Cyclization: Depending on the structure of the compound and the reaction conditions, intramolecular cyclization reactions may occur, leading to the formation of cyclic products.
Grignard Reactions: The compound can react with Grignard reagents to introduce various alkyl or aryl groups to the molecule.
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Methyl 5-(benzyloxy)-1H-indole-2-carboxylate
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Ethyl 5-(benzyloxy)-1H-indole-2-carboxylate
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Methyl 5-(benzyloxy)-2-methyl-1H-indole-3-carboxylate
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5-(Benzyloxy)-1H-indole-2-carboxylic acid
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