Catalysts Ligands Chiral Oxygen Ligands BINOLs

BINOLs

BINOL (1,1′-bi-2-naphthol) ligands are a class of axially chiral diol compounds that possess a C₂-symmetric biaryl backbone. The axial chirality arises from restricted rotation around the bond connecting the two naphthyl units. BINOL and its derivatives have found widespread use in asymmetric catalysis, particularly as chiral auxiliaries, Brønsted acid catalysts, and precursors to other ligand types such as phosphoric acids and phosphoramidites. BINOL derivatives are widely used in enantioselective reactions, including asymmetric hydrogenation, allylation, and the addition of nucleophiles to carbonyl compounds. One of the most impactful applications is in chiral Brønsted acid catalysis, where BINOL-derived phosphoric acids (e.g., TRIP) enable a wide variety of enantioselective transformations such as Mannich, Friedel–Crafts, and Diels–Alder reactions. The hydroxyl groups on BINOL can also be modified to introduce phosphorus or boron functionalities, broadening its scope in Lewis acid catalysis. Moreover, BINOL-based ligands are used in metal complexes with Ti, Al, or Ru in asymmetric allylation and other C–C bond-forming reactions. Due to its high modularity, rigid structure, and proven efficiency, BINOL remains a cornerstone ligand in modern asymmetric synthesis.
Further Reading:
Typically In Stock
Purity
  • Please Select
  • 99+%
  • 99%
  • 98+%
  • 98%
  • 97+%
  • 97%
  • 96+%
  • 96%
  • 95+%
  • 95%
  • 93%
  • 90+%
  • 90%
Size
  • Please Select
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1g
  • 5g
  • 10g
  • 25g
  • 100g
  • 500g
  • 1000g
  • 1kg
Clear Filters
(R)-3,3'-Bis(4-chlorophenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A1188919851615-05-998%

(R)-3,3'-Bis(4-chlorophenyl)-[1,1'-binaphthalene]-2,2'-diol

$40.00/100mg

Detail
(R)-3,3'-Bis(4-(tert-butyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A499734851615-06-098% 99%ee

(R)-3,3'-Bis(4-(tert-butyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol

$59.00/100mg

Detail
(S)-3,3'-Bis[4-(trifluoromethyl)phenyl]-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A11478881621066-21-498% 99%ee

(S)-3,3'-Bis[4-(trifluoromethyl)phenyl]-[1,1'-binaphthalene]-2,2'-diol

$30.00/100mg

Detail
(R)-3,3'-Bis(2,4,6-triisopropylphenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A829680247123-09-797%

(R)-3,3'-Bis(2,4,6-triisopropylphenyl)-[1,1'-binaphthalene]-2,2'-diol

$137.00/100mg

Detail
(S)-3,3'-Bis(4-chlorophenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A11882361204609-08-498%

(S)-3,3'-Bis(4-chlorophenyl)-[1,1'-binaphthalene]-2,2'-diol

$42.00/100mg

Detail
(S)-3,3'-Diphenyl-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A847689102490-05-195% 99%ee

(S)-3,3'-Diphenyl-[1,1'-binaphthalene]-2,2'-diol

$33.00/100mg

Detail
(R)-3,3'-Bis(3,5-dimethylphenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A216163215433-51-598% 99%ee

(R)-3,3'-Bis(3,5-dimethylphenyl)-[1,1'-binaphthalene]-2,2'-diol

$81.00/100mg

Detail
(R)-3,3'-Diphenyl-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A12684775684-93-497% 99%ee

(R)-3,3'-Diphenyl-[1,1'-binaphthalene]-2,2'-diol

$58.00/100mg

Detail
(S)-3,3'-Bis(3,5-dimethylphenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A459203435327-17-698% 99%ee

(S)-3,3'-Bis(3,5-dimethylphenyl)-[1,1'-binaphthalene]-2,2'-diol

$90.00/100mg

Detail
(S)-3,3'-Bis(4-(tert-butyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A442649309934-84-798% 99%ee

(S)-3,3'-Bis(4-(tert-butyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol

$67.00/100mg

Detail
(R)-3,3'-Bis[4-(trifluoromethyl)phenyl]-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A276989791616-58-598%

(R)-3,3'-Bis[4-(trifluoromethyl)phenyl]-[1,1'-binaphthalene]-2,2'-diol

$79.00/100mg

Detail
(S)-2,2'-Dimethoxy-3,3'-diphenyl-1,1'-binaphthalene

click to sign in and save

A109094212191-84-998%

(S)-2,2'-Dimethoxy-3,3'-diphenyl-1,1'-binaphthalene

$177.00/100mg

Detail
(R)-3,3'-Bis(3,5-bis(trifluoromethyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A822395756491-54-098%

(R)-3,3'-Bis(3,5-bis(trifluoromethyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol

$35.00/50mg

Detail
(R)-3,3'-Bis(4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A155163756491-51-798%

(R)-3,3'-Bis(4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol

$46.00/100mg

Detail
(S)-3,3'-Bis(3,5-bis(trifluoromethyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A349404849939-13-598% 99%ee

(S)-3,3'-Bis(3,5-bis(trifluoromethyl)phenyl)-[1,1'-binaphthalene]-2,2'-diol

$20.00/50mg

Detail
(S)-3,3'-Bis(2,4,6-triisopropylphenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A230826908338-44-398%

(S)-3,3'-Bis(2,4,6-triisopropylphenyl)-[1,1'-binaphthalene]-2,2'-diol

$29.00/100mg

Detail
(R)-2,2'-Dimethoxy-3,3'-diphenyl-1,1'-binaphthalene

click to sign in and save

A668109219757-68-398%

(R)-2,2'-Dimethoxy-3,3'-diphenyl-1,1'-binaphthalene

$195.00/100mg

Detail
(S)-3,3'-Bis(4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol

click to sign in and save

A6413631199631-29-298%

(S)-3,3'-Bis(4-methoxyphenyl)-[1,1'-binaphthalene]-2,2'-diol

$17.00/100mg

Detail
(R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl-3,3'-diboronic acid pinacol ester

click to sign in and save

A449432260442-17-997% 99%ee

(R)-2,2'-Bis(methoxymethoxy)-1,1'-binaphthyl-3,3'-diboronic acid pinacol ester

$127.00/100mg

Detail
(2,2'-Dimethoxy-[1,1'-binaphthalene]-3,3'-diyl)diboronic acid

click to sign in and save

A145146220204-00-298%

(2,2'-Dimethoxy-[1,1'-binaphthalene]-3,3'-diyl)diboronic acid

$70.00/250mg

Detail
1 2 3    page 1 of 3 Pages

Inquiry