Chemistry Organic Building Blocks Fluorinated Building Blocks 2,5-difluorobenzoic acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—COOH).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Esterification: Benzoic acid can undergo esterification reactions with 【alcohols|https://www.ambeed.com/alcohols.html】 in the presence of a catalyst, typically an acid catalyst like sulfuric acid. This reaction leads to the formation of benzoate 【esters|https://www.ambeed.com/esters.html】 and water.
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