Home Chemistry Organic Building Blocks Iodides Ethyl 3-Iodobenzoate
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —I,—COOC2H5).
Cross-Coupling Reactions: Iodobenzene is commonly used in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling an aryl halide (like iodobenzene) with an organometallic reagent, leading to the formation of new carbon-carbon bonds.
Fischer Esterification: Ethyl benzoate can be synthesized through Fischer esterification, a reaction between benzoic acid and ethanol in the presence of an acid catalyst, usually sulfuric acid (H2SO4): C6H5COOH + C2H5OH → C6H5COOC2H5 + H2O
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Ethyl 2-amino-5-iodo-4-(trifluoromethyl)benzoate
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