FPP synthase (Farnesyl pyrophosphate synthase) is a key member of the enzyme family responsible for synthesizing Farnesyl pyrophosphate (FPP), an essential intermediate in biosynthetic pathways. Composed of multiple structural domains, it is primarily located in the endoplasmic reticulum and involved in synthesizing crucial molecules like cholesterol and ubiquinones. The enzyme catalyzes the production of FPP from isopentenyl pyrophosphate (IPP) and dimethylallyl pyrophosphate (DMAPP), affecting cell growth and differentiation signaling pathways. Its gene expression significantly varies across different tissues, and mutations or aberrant expressions are associated with various diseases, including cancer and metabolic disorders.