Histidine

Histidine

Histidine, denoted by the symbols His or H, is a vital amino acid utilized in protein synthesis. It comprises an α-amino group, a carboxylic acid group, and an imidazole side chain. This composition classifies histidine as a positively charged amino acid at physiological pH. Initially believed to be indispensable solely for infants, further studies have demonstrated its essentiality for adults as well. Histidine is an amino acid most people get from food. It's used in growth, repair of damaged tissues, and making blood cells. It helps protect nerve cells. It's used by the body to make histamine. Histidine is biosynthesized through the conversion of phosphoribosyl pyrophosphate (PRPP), a molecule derived from ribose-5-phosphate. This conversion is facilitated by the enzyme ribose-phosphate diphosphokinase, which operates within the pentose phosphate pathway. The genetic code uses the codons CAU and CAC to encode histidine.

Structure
CAS Number 71-00-1
Classification

The basic (positively charged) amino acids include

Arginine

Lysine

Histidine
Categories
Histidine biosynthesis Related Compounds
5-Phospho-alpha-D-ribose 1-diphosphate
1-(5-Phospho-D-ribosyl)-ATP
Phosphoribosyl-AMP
5-(5-Phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide
N-(5'-Phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-D-ribosyl)-4-imidazolecarboxamide
D-erythro-1-(Imidazol-4-yl)glycerol 3-phosphate
3-(Imidazol-4-yl)-2-oxopropyl phosphate
25679-93-0 L-Histidinol phosphate
4836-52-6 L-Histidinol
L-Histidinal
71-00-1 L-Histidine

Histidine and Derivatives:

Histidine:

Derivatives: