Piperidine plays a crucial role as a fundamental heterocyclic structure and serves as a critical foundation in drug manufacturing. Variations of piperidine are employed in diverse applications, including their use as agents for combating cancer, viruses, malaria, microbes, fungi, hypertension, pain, inflammation, Alzheimer's disease, psychosis, and/or blood clot prevention.

Drug Structure Target Drug Categories
Icaridin Unknown Insect Repellents

Related Products:

Drug Structure Target Drug Categories
Paroxetine SERT Antidepressive Agents

Related Products:

Drug Structure Target Drug Categories
Melperone D2 dopaminergic, 5-HT2A Antipsychotic Agents

Related Products:

Drug Structure Target Drug Categories
Pitolisant human H3 receptor Histamine Antagonists

Related Intermediates:

Related Products:

Example Reaction of Piperidines:

Hofmann exhaustive methylation:

More >

Categories:

See also:

References:

[1]Abdelshaheed M M, Fawzy I M, El-Subbagh H I, et al. Piperidine nucleus in the field of drug discovery[J]. Future Journal of Pharmaceutical Sciences, 2021, 7: 1-11.

[2]Goel P, Alam O, Naim M J, et al. Recent advancement of piperidine moiety in treatment of cancer-A review[J]. European Journal of Medicinal Chemistry, 2018, 157: 480-502.

[3]Pourshojaei Y, Abiri A, Eskandari K, et al. Phenoxyethyl piperidine/morpholine derivatives as PAS and CAS inhibitors of cholinesterases: insights for future drug design[J]. Scientific Reports, 2019, 9(1): 19855.