Chemistry Heterocyclic Building Blocks Indolines

Indolines

Indoline is a type of organic compound that is aromatic and heterocyclic, having the chemical formula C8H9N. Its structure is composed of two rings, a six-membered benzene ring and a five-membered ring containing nitrogen, which are fused together to form a bicyclic structure.

Indoline has a structure similar to indole, except for a saturated 2-3 bond. When subjected to oxidation/dehydrogenation, it can be transformed into indoles.

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(E)-[3,3'-biindolinylidene]-2,2'-dione (Z)-3-((1H-pyrrol-2-yl)methylene)indolin-2-one (Z)-3-(phenyl(phenylamino)methylene)indolin-2-one (Z)-3-benzylideneindolin-2-one 1-(indolin-1-yl)ethan-1-one 1-benzylindoline-2,3-dione 1-methylindolin-2-one 1-methylindoline 1-methylindoline-2,3-dione 2-(1,3-dioxoisoindolin-2-yl)propanoic acid 2-methylindoline 2-methylisoindolin-1-one 3,3-dimethylindolin-2-one 3,3-dimethylindoline 4-bromoindoline 4-chloroindoline-2,3-dione 4-methylindoline 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indoline 5-bromoindolin-2-one 5-bromoindoline 5-bromoisoindoline-1,3-dione 5-chloroindolin-2-one 5-fluoroindoline 5-methoxyindoline 5-methylindolin-2-one 5-methylindoline 6-bromoindolin-2-one 6-bromoindoline-2,3-dione 6-chloroindolin-2-one 6-chloroindoline 6-chloroindoline-2,3-dione 6-fluoroindolin-2-one 6-fluoroindoline-2,3-dione 7-bromoindoline 7-fluoroindolin-2-one 7-fluoroindoline-2,3-dione 7-methylindoline-2,3-dione indoline-2-carboxylic acid methyl indoline-6-carboxylate spiro[cyclopropane-1,3'-indolin]-2'-one tert-butyl indoline-1-carboxylate

By Key Group+−

aminoindoline aminoisoindoline bromoindoline bromoisoindolin bromoisoindoline chloroindolin chloroisoindoline dibromoindoline dichloroindoline difluoroindoline dimethylindoline dioxaborolane-indoline dioxoindoline dioxoisoindolin fluoroindolin fluoroindoline fluoroisoindoline hydroxy-indoline hydroxyindolin hydroxyisoindolin indolin-one indoline-carboxylate indoline-carboxylic acid indoline-carboxylic-acid indoline-nitrile indoline-oxazine indoline-piperidine isoindolin isoindoline methoxyindoline methoxyisoindoline methylindoline methylisoindoline nitroindolin nitroindoline nitroisoindoline oxoindoline oxoisoindoline spiro-indoline-piperidine trifluoromethyl-indoline

By Parent Nucleus+−

Aromatic Heterocycles Dioxolanes Epoxides Indoles Morpholines Other Aromatic Heterocycles Piperidines Pyridazines Pyridines Pyrimidines Pyrroles Spiroes Tetrahydropyrans Thiazoles Thiophenes

By Functional Group+−

Alcohols Aldehydes Alkenyls Alkyls Alkynyls Amides Amines Aryls Bromides Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Hydrazines Hydroxylamines Iodides Ketones Nitriles Nitroes Phenols Trifluoromethyls

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    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    2-((7-Bromo-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)isoindoline-1,3-dione

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    A16041172629316-05-695%

    2-((7-Bromo-4-oxo-3,4-dihydrophthalazin-1-yl)methyl)isoindoline-1,3-dione

    $1052.00/5g

    Detail
    2-Oxoindoline-4-carbonitrile

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    A255398214759-51-098%

    2-Oxoindoline-4-carbonitrile

    $60.00/100mg

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    Methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate

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    A9801161168152-07-596%

    Methyl (3E)-1-acetyl-3-[methoxy(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate

    $22.00/100mg

    Detail
    tert-Butyl 5-methoxy-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate

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    A136273752234-64-398%

    tert-Butyl 5-methoxy-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate

    $116.00/50mg

    Detail
    5,6-Difluoroindolin-2-one

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    A37236471294-07-095%

    5,6-Difluoroindolin-2-one

    $135.00/5g

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    1-(2-Methoxyethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indoline

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    A4390511704069-52-298+%

    1-(2-Methoxyethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indoline

    $68.00/100mg

    Detail
    4-Methoxyisoindolin-1-one

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    A167996366453-22-795%

    4-Methoxyisoindolin-1-one

    $24.00/250mg

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    2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)isoindoline-1,3-dione

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    A315652138500-87-595%

    2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)isoindoline-1,3-dione

    $16.00/250mg

    Detail
    5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one

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    A463807837392-64-096%

    5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indolin-2-one

    $83.00/5g

    Detail
    Methyl 2,3-dioxoindoline-6-carboxylate

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    A396878213670-35-098%

    Methyl 2,3-dioxoindoline-6-carboxylate

    $162.00/1g

    Detail
    tert-Butyl 5-bromoindoline-1-carboxylate

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    A770966261732-38-197%

    tert-Butyl 5-bromoindoline-1-carboxylate

    $212.00/25g

    Detail
    tert-Butyl 2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

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    A201457205383-87-595%

    tert-Butyl 2-oxospiro[indoline-3,3'-pyrrolidine]-1'-carboxylate

    $19.00/100mg

    Detail
    2-(2,3-Dioxoindolin-1-yl)acetic acid

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    A62190560705-96-695%

    2-(2,3-Dioxoindolin-1-yl)acetic acid

    $13.00/100mg

    Detail
    1-(2-Chlorobenzyl)indoline-2,3-dione

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    A600611306279-75-497%

    1-(2-Chlorobenzyl)indoline-2,3-dione

    $39.00/100mg

    Detail
    Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate

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    A8472476974-10-398%

    Ethyl 2-(1,3-dioxoisoindolin-2-yl)acetate

    $72.00/1g

    Detail
    Methyl indoline-4-carboxylate hydrochloride

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    A7401481187927-40-797%

    Methyl indoline-4-carboxylate hydrochloride

    $29.00/100mg

    Detail
    tert-Butyl 5-chloro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate

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    A1271242103402-31-797%

    tert-Butyl 5-chloro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate

    $584.00/5g

    Detail
    6-Bromo-3,3-dimethylindolin-2-one

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    A160992158326-84-295%

    6-Bromo-3,3-dimethylindolin-2-one

    $41.00/250mg

    Detail
    5-Aminoisoindolin-1-one

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    A254099222036-66-098%

    5-Aminoisoindolin-1-one

    $38.00/250mg

    Detail
    5-Bromo-3,3-dimethylindolin-2-one

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    A659376120902-45-698%

    5-Bromo-3,3-dimethylindolin-2-one

    $153.00/5g

    Detail
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