Home Chemistry Heterocyclic Building Blocks Indazoles Methyl 1H-Indazole-7-Carboxylate
Nucleophilic Substitution: The carboxylate group can undergo nucleophilic substitution reactions, such as ester hydrolysis or substitution with nucleophiles like amines or thiols.
Esterification: The carboxylate group can react with alcohols in the presence of acid catalysts to form esters.
Amide Formation: The carboxylate group can react with amines to form amides.
Hydrogenation: The carbon-carbon double bond in the indazole ring can be hydrogenated to yield the corresponding saturated derivative.
Nucleophilic Addition: The indazole ring can undergo nucleophilic addition reactions with various electrophiles, leading to the formation of functionalized derivatives.
Ring-closure Reactions: The indazole ring can undergo ring-closure reactions under certain conditions to form cyclic compounds.
Substitution Reactions: The indazole ring can undergo substitution reactions, such as halogenation, nitration, or sulfonation.
Oxidation: The methyl group or other alkyl substituents can be oxidized to form corresponding alcohols, ketones, or carboxylic acids.
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Methyl 6-amino-1H-indazole-7-carboxylate
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Methyl 5-nitro-1H-indazole-7-carboxylate
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Methyl 5-bromo-1H-indazole-7-carboxylate
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Methyl 5-chloro-1H-indazole-7-carboxylate
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Methyl 4-chloro-1H-indazole-7-carboxylate
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