Home Life Science Inhibitors/Agonists Stem Cells PORCN
Functioning as a membrane-bound O-acyltransferase, Porcn assumes a crucial role in palmitoylating Wnt ligands and facilitating their subsequent secretion. Apart from its involvement in stem cell signaling and differentiation, recent discoveries highlight Porcn's contribution to the development and progression of colorectal, pancreatic, liver, head, and neck cancers. The development of small molecule inhibitors has also introduced a promising avenue for strategies in cancer treatment.
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