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Chemical Structure| 63879-04-9 Chemical Structure| 63879-04-9

Structure of 63879-04-9

Chemical Structure| 63879-04-9

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Product Details of [ 63879-04-9 ]

CAS No. :63879-04-9
Formula : C7H13NO3
M.W : 159.18
SMILES Code : CC(C)(NC(C)=O)CC(O)=O
MDL No. :MFCD00154639

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Application In Synthesis of [ 63879-04-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 63879-04-9 ]

[ 63879-04-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 625-05-8 ]
  • [ 108-24-7 ]
  • [ 63879-04-9 ]
YieldReaction ConditionsOperation in experiment
With dmap; triethylamine; In tetrahydrofuran; at 60℃; for 3h; Triethylamine (1.8 ml_, 12.8 mmol), acetic anhydride (1.2 mL, 12.8 mL) and DMAP (10 mg, 0.09 mmol) are subsequentially added to a suspension of 3-amino-3-methyl-butyric acid (1.00 g, 8.5 mmol) in THF (100 mL). After heating at 60°C for 3 h AcOEt is added and the organic phase is washed with 1N HCI. Drying (Na2SO4), filtration and evaporation of the solvent yields the desired product. MS (LC-MS): [M+Hf= 160.1. tR (HPLC, Waters Symmetry C18 column, 20-95percent CH3CN/H2O/3.5 min, 95percent CH3CN/H2O, 2 min, CH3CN and H2O containing 0.1percent TFA, flow: 0.6 ml_/min): 0.40 min.
 

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