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CAS No. : | 1017221-34-9 | MDL No. : | MFCD09882493 |
Formula : | C11H18N4O | Boiling Point : | - |
Linear Structure Formula : | - | InChI Key : | PCBIQPFJSIIXGG-UHFFFAOYSA-N |
M.W : | 222.29 | Pubchem ID : | 24253284 |
Synonyms : |
|
Signal Word: | Warning | Class: | |
Precautionary Statements: | P280-P305+P351+P338 | UN#: | |
Hazard Statements: | H317-H319 | Packing Group: | |
GHS Pictogram: |
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
Yield | Reaction Conditions | Operation in experiment |
---|---|---|
80.7% | With hydrogenchloride; iron In ethanol; water at 80℃; for 3h; | 5 4.1.11. General procedure for preparation of compounds (18a-c, 18d-g,19a-g, 20a-c and 21a-c) General procedure: To the solution of 14a-c, 14e-g, 15a-g, 16a-c or 17a-c (0.005mol) in ethanol/water (9:1, 30mL) was added hydrochloric acid (1.0mL) and iron powder (1.12g, 0.02mol). The resulting mixture was heated at 80°C for 3h, filtered through celite and concentrated to remove ethanol. The aqueous solution was extracted with ethyl acetate (3×100mL) and the combined organic layers were washed with water, brine, dried over Na2SO4 and concentrated to gain 18a-c, 18e-g, 19a-g, 20a-c or 21a-c |
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