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Chemical Structure| 103926-64-3 Chemical Structure| 103926-64-3

Structure of Sepimostat
CAS No.: 103926-64-3

Chemical Structure| 103926-64-3

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Sepimostat exerts neuroprotective effects by antagonizing NR2B N-methyl-D-aspartate receptors, acting on the Ifenprodil binding site of the NR2B subunit, with a Ki value of 27.7 μM for inhibiting Ifenprodil binding.

Synonyms: FUT-187 free base

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Product Details of Sepimostat

CAS No. :103926-64-3
Formula : C21H19N5O2
M.W : 373.41
SMILES Code : O=C(OC1=CC=C2C=C(C(N)=N)C=CC2=C1)C3=CC=C(NC4=NCCN4)C=C3
Synonyms :
FUT-187 free base
MDL No. :MFCD00868988
InChI Key :QMRJOIUGPCVZPH-UHFFFAOYSA-N
Pubchem ID :108041

Safety of Sepimostat

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Biological Activity

Description
Sepimostat demonstrates neuroprotective effects through antagonism of the NR2B N-methyl-D-aspartate receptor at the Ifenprodil-binding site of the NR2B subunit. Sepimostat inhibits Ifenprodil binding with a Ki value of 27.7 µM [1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.68mL

0.54mL

0.27mL

13.39mL

2.68mL

1.34mL

26.78mL

5.36mL

2.68mL

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