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Chemical Structure| 1051387-90-6 Chemical Structure| 1051387-90-6

Structure of SPI-112
CAS No.: 1051387-90-6

Chemical Structure| 1051387-90-6

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SPI-112 is a potent, selective and competitive SHP2 (PTPN11) inhibitor with IC50s of 1 μM, 18.3 μM and 14.5 μM for SHP2, protein tyrosine phosphatase (PTP) and PTP1B, respectively.

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