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Chemical Structure| 10521-06-9 Chemical Structure| 10521-06-9

Structure of 10521-06-9

Chemical Structure| 10521-06-9

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Product Details of [ 10521-06-9 ]

CAS No. :10521-06-9
Formula : C8H12O3
M.W : 156.18
SMILES Code : O=C(CCCCCC1)OC1=O
MDL No. :MFCD18253479

Safety of [ 10521-06-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 10521-06-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 10521-06-9 ]

[ 10521-06-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1119-34-2 ]
  • [ 10521-06-9 ]
  • suberoyl arginine [ No CAS ]
YieldReaction ConditionsOperation in experiment
With water; sodium hydrogencarbonate; at 4℃; for 0.333333h; General procedure for the preparation of the SA derivatives: To a solution of amino acid hydrochloride (1 equiv) and sodium bicarbonate (2 equiv) in water (ca. 1 M) was added the carboxylic anhydride (1.1 equiv) at 4 C slowly. After stirring for 20 min, a few drops of concentrated ammonia-water were added to adjust the pH to 8. The solution was then filtered and washed three times with dichloromethane. The sample was freeze-dried and purified by CI 8 reverse-phase silica gel chromatography. Suberoyl arginine: 'H NMR (500 MHz, D20) delta 4.19-4.17 (dd, 1H), 3.03 (t, 2H), 2.19 (t, 2H), 2.11 (t, 2H), 1.79-1.71 (m, 1H), 1.62-1.55 (m, 1H), 1.49-1.37 (m, 6H), 1.14-1.12 (m, 4H); XH NMR (500 MHz, DMSO-i) delta 4.14-4.11 (dd, 1H), 3.09 (t, 2H), 2.17 (t, 2H), 2.10 (t, 2H), 1.71-1.67 (m, 1H), 1.62-1.57 (m, 1H), 1.49 (m, 6H), 1.22 (m, 4H); 13C NMR (125 MHz, D20) delta 179.2, 177.3, 175.5, 156.6, 52.3, 40.6, 35.3, 33.8, 27.9, 27.8, 27.7, 25.2, 24.6, 24.3; 13C NMR (125 MHz, DMSO-i) delta 175.3, 174.1, 173.5, 157.2, 52.0, 39.3, 35.6, 28.9, 28.5, 25.9, 25.8, 25.0; MS(APCI) calcd for Ci4H27N405 (M+H)+ 331.2, found 331.1; calcd for Ci4H25N405 (M-fff 329.2, found 329.2.
 

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