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Chemical Structure| 107902-67-0 Chemical Structure| 107902-67-0

Structure of Tazofelone
CAS No.: 107902-67-0

Chemical Structure| 107902-67-0

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Tazofelone is a new inflammatory bowel disease agent.

Synonyms: LY 213829

4.5 *For Research Use Only !

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Product Details of Tazofelone

CAS No. :107902-67-0
Formula : C18H27NO2S
M.W : 321.48
SMILES Code : O=C1NCSC1CC2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2
Synonyms :
LY 213829
MDL No. :MFCD00868113
InChI Key :ILMMRHUILQOQGP-UHFFFAOYSA-N
Pubchem ID :68745

Safety of Tazofelone

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Isoform Comparison

Biological Activity

Description
Tazofelone (LY 213829) functions as a cyclooxygenase-II (COX-II) inhibitor and undergoes transformation into sulfoxide and quinol metabolites primarily mediated by CYP3A. It is utilized in research related to inflammatory bowel disease [1][2].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.11mL

0.62mL

0.31mL

15.55mL

3.11mL

1.56mL

31.11mL

6.22mL

3.11mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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