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Chemical Structure| 1126084-37-4 Chemical Structure| 1126084-37-4

Structure of ASP-9521
CAS No.: 1126084-37-4

Chemical Structure| 1126084-37-4

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ASP 9521 is a potent and selective AKR1C3 inhibitor with IC50 of 11 nM for human AKR1C3.

4.5 *For Research Use Only !

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Product Details of ASP-9521

CAS No. :1126084-37-4
Formula : C19H26N2O3
M.W : 330.42
SMILES Code : O=C(N1CCC(CC1)CC(C)(O)C)C2=CC3=CC(OC)=CC=C3N2
MDL No. :MFCD30532740
InChI Key :OXSCPDKUZWPWFR-UHFFFAOYSA-N
Pubchem ID :25210792

Safety of ASP-9521

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT01352208 Castrate Resistant Prostate Ca... More >>ncer Less << Phase 1 Phase 2 Terminated(It was decided to d... More >>iscontinue the development in consideration of the results of a P1 study) Less << - Belgium ... More >> Site 131 Antwerp, Belgium, 2650 France Site: 121 Villejuif, France United Kingdom Site:109 Glasgow, United Kingdom Site: 101 Surrey, United Kingdom Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.03mL

0.61mL

0.30mL

15.13mL

3.03mL

1.51mL

30.26mL

6.05mL

3.03mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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