Home Cart 0 Sign in  

[ CAS No. 1133-72-8 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1133-72-8
Chemical Structure| 1133-72-8
Structure of 1133-72-8 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 1133-72-8 ]

Related Doc. of [ 1133-72-8 ]

Alternatived Products of [ 1133-72-8 ]
Product Citations

Product Details of [ 1133-72-8 ]

CAS No. :1133-72-8 MDL No. :MFCD00466278
Formula : C11H8O3 Boiling Point : -
Linear Structure Formula :C9H5(O)2C(O)CH3 InChI Key :-
M.W : 188.18 Pubchem ID :-
Synonyms :

Safety of [ 1133-72-8 ]

Signal Word:Warning Class:
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 UN#:
Hazard Statements:H302-H315-H319 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1133-72-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1133-72-8 ]

[ 1133-72-8 ] Synthesis Path-Downstream   1~7

  • 1
  • [ 7755-70-6 ]
  • [ 1133-72-8 ]
  • [ 23824-59-1 ]
  • 2
  • [ 50-00-0 ]
  • [ 142-64-3 ]
  • [ 1133-72-8 ]
  • [ 119712-33-3 ]
  • 3
  • [ 15454-54-3 ]
  • [ 1133-72-8 ]
  • [ 130749-12-1 ]
  • 4
  • [ 10024-93-8 ]
  • [ 1251-85-0 ]
  • [ 1133-72-8 ]
  • Nd(3+)*3C9H4O2COCH3(1-)*C23H24N4O2=Nd(C9H4O2COCH3)3(C23H24N4O2) [ No CAS ]
  • 5
  • [ 1133-72-8 ]
  • [ 125096-15-3 ]
  • [ 1414632-92-0 ]
YieldReaction ConditionsOperation in experiment
79% In N,N-dimethyl acetamide; at 70.0℃; General procedure: A mixture of acylhydrazine 1, 2 or alkylhydrazine 3 (10 mmol) and cyclic di- or triketones (2-acetylcyclohexanone 19, 2-acetyl-1,3-cyclohexandione 20 or 2-acetyl-1,3-indandione 21) (10 mmol) in DMA was stirred at 70C for 4 to 8h, until the complete consumption of the reagents (reaction progress monitored by TLC). After cooling to rt, distilled water was added to the reaction media and the resulting solid was colected by filtration and purified by column chromatography on silica gel using EtOAc/n-C6H14 1/1 as eluent to afford purepyrazole (22-30).
  • 6
  • [ 4871-25-4 ]
  • [ 1133-72-8 ]
  • [ 1609240-19-8 ]
YieldReaction ConditionsOperation in experiment
91% In ethanol Reflux;
  • 7
  • [ 23489-36-3 ]
  • [ 79-19-6 ]
  • [ 1133-72-8 ]
  • 1-(4-(benzofuran-2-yl)thiazol-2-yl)-3-methylindeno[1,2-c]pyrazol-4(1H)-one [ No CAS ]
YieldReaction ConditionsOperation in experiment
63% Stage #1: thiosemicarbazide; 2-acetyl-indan-1,3-dione In methanol Reflux; Stage #2: 1-(benzofuran-2-yl)-2-bromoethan-1-one With sodium acetate; acetic acid In methanol for 7h; Reflux; 4.1.2. General procedure for the synthesis of indenopyrazoles 3(a-l ) General procedure: The starting material 2-acyl-(1 H )-indene1,3(2 H )-diones 1(a-d ) were prepared by Claisen condensation of equimolar quantities of diethylphthalate and appropriate methylketones in presence of freshly prepared sodium methoxide and dry methanol as reported in the literature [ 78 , 79 ]. Next, a solution of 2-acyl-(1 H )-indene- 1,3(2 H )diones (1 mmol) 1(a-d ) and thiosemicabazide (1 mmol) ( 2 ) in dry methanol (30 mL) was taken in a 250 mL round bottomed flask equipped with a reflux condenser with guard tube and re- fluxed for 10-15 min on a water bath. Subsequently, appropriate - bromoketones (5 mmol) and sodium acetate (5 mmol) were added slowly to the above reaction mixture while stirring on a mag- netic stirrer followed by addition of methanol:glacial acetic acid (2:1, v/v) (20 mL) and refluxing for 5-8 h. The progress of reaction was monitored by thin layer chromatography on the aliquots with- drawn from the reaction mixture at different intervals of time. On completion of the reaction, the solid separated out which was fil- tered and purified by column chromatography on silica gel (60-120 mesh) using hexane/EtOAc (9:1, v/v) as eluent to afford the corre- sponding indenopyrazoles 3(a-l) in good yields (53-80%).
Recommend Products
Same Skeleton Products
Historical Records