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[ CAS No. 1167418-12-3 ]

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Chemical Structure| 1167418-12-3
Chemical Structure| 1167418-12-3
Structure of 1167418-12-3 * Storage: {[proInfo.prStorage]}

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Alternatived Products of [ 1167418-12-3 ]

Product Details of [ 1167418-12-3 ]

CAS No. :1167418-12-3 MDL No. :MFCD18837754
Formula : C12H15BN2O4 Boiling Point : 455.6°C at 760 mmHg
Linear Structure Formula :- InChI Key :N/A
M.W :262.07 g/mol Pubchem ID :-
Synonyms :

Safety of [ 1167418-12-3 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 1167418-12-3 ]

  • Downstream synthetic route of [ 1167418-12-3 ]

[ 1167418-12-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 338454-14-1 ]
  • [ 24424-99-5 ]
  • [ 1167418-12-3 ]
YieldReaction ConditionsOperation in experiment
68% With dmap; triethylamine; In acetonitrile; at 25℃; A solution of <strong>[338454-14-1](1H-indazol-5-yl)boronic acid</strong> (300 mg, 1.85 mmol, 1.00 equiv), triethylamine (280 mg), Boc2O (804 mg, 3.68 mmol, 1.99 equiv) and 4-dimethylaminopyridine (23 mg, 0.19 mmol, 0.10 equiv) in acetonitrile (15 mL) was stirred at 25 C. overnight. Water (20 mL) was then added and the resulting mixture was extracted with 3×60 mL of ethyl acetate. The combined organic extracts was washed with 2×3 mL of water and 3×3 mL of brine. The organic layer was dried over anhydrous sodium sulfate and concentrated under vacuum. The residue was purified on a silica gel column eluted with 0-5% of methanol in dichloromethane to give 320 mg (68%) of 1-(tert-butoxycarbonyl)-<strong>[338454-14-1]1H-indazol-5-ylboronic acid</strong> as a white solid. LCMS (method A, ESI): RT=1.34 min, m/z=263.0 [M+H]+.
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