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Chemical Structure| 1199590-75-4 Chemical Structure| 1199590-75-4

Structure of GNE 220
CAS No.: 1199590-75-4

Chemical Structure| 1199590-75-4

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GNE-220 is a potent and selective inhibitor of MAP4K4 with an IC50 of 7 nM, also inhibits MINK (MAP4K6), DMPK and KHS1 (MAP4K5) with IC50 of 9 nM, 476 nM and 1,110 nM.

Synonyms: GNE 220

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Product Details of GNE 220

CAS No. :1199590-75-4
Formula : C25H26N8
M.W : 438.53
SMILES Code : CN1C=C(C2N=C3C4C(=NC=C(C=4)C4C=CC(N5CCN(C)CC5)=CC=4)NC3=C(C)N=2)C=N1
Synonyms :
GNE 220
MDL No. :MFCD31619318

Safety of GNE 220

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Related Pathways of GNE 220

MAPK
Hippo

Isoform Comparison

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2.28mL

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2.28mL

 

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