Home Cart Sign in  
Chemical Structure| 1215281-19-8 Chemical Structure| 1215281-19-8

Structure of YK-3-237
CAS No.: 1215281-19-8

Chemical Structure| 1215281-19-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

YK-3-237 is a SIRT1 activator targeting mutant p53 (mtp53). It inhibits the proliferation of triple-negative breast cancer cells by reducing mtp53 acetylation. This compound shows significant potential in cancer treatment research, particularly for triple-negative breast cancer.

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of YK-3-237

CAS No. :1215281-19-8
Formula : C19H21BO7
M.W : 372.18
SMILES Code : COC1=C(OC)C(OC)=CC(C(/C=C/C2=CC=C(OC)C(B(O)O)=C2)=O)=C1
MDL No. :MFCD28167612
InChI Key :AKNGHUAJAODDJA-FNORWQNLSA-N
Pubchem ID :24881094

Safety of YK-3-237

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Related Pathways of YK-3-237

epigenetics

Isoform Comparison

Biological Activity

Description
YK-3-237 is a SIRT1 activator, specifically targets mutant p53 and curtails the growth of triple-negative breast cancer (TNBC) cells[1].

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.69mL

0.54mL

0.27mL

13.43mL

2.69mL

1.34mL

26.87mL

5.37mL

2.69mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

References

 

Historical Records

Categories