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[ CAS No. 1239576-61-4 ] {[proInfo.proName]}

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Cat. No.: {[proInfo.prAm]}
Chemical Structure| 1239576-61-4
Chemical Structure| 1239576-61-4
Structure of 1239576-61-4 * Storage: {[proInfo.prStorage]}
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Product Details of [ 1239576-61-4 ]

CAS No. :1239576-61-4 MDL No. :
Formula : C14H19F2NO3 Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 287.30 Pubchem ID :-
Synonyms :

Safety of [ 1239576-61-4 ]

Signal Word:Warning Class:
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338 UN#:
Hazard Statements:H302-H315-H319-H335 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1239576-61-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1239576-61-4 ]

[ 1239576-61-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 198474-90-7 ]
  • [ 1239576-61-4 ]
YieldReaction ConditionsOperation in experiment
74% Preparation 1; Preparation of 2-[(2S)-2-amino-3-(3,4-difluorophenyl)propyl1-1 /-/-isoindole-1 ,3(2H)-dione; a) 1 ,1-dimethylethyl [(1 S)-2-(3,4-difluorophenyl)-1-(hydroxymethyl)ethyl]carbamate; To a solution of Lambda/-[(1 ,1-dimethylethyl)oxy]carbonyl}-3,4-difluoro-L-phenylalanine (2.0 g, 6.7 mmol) in THF (35 ml.) at 0 0C stirred was added BH3-THF (30 ml_, 30 mmol- 1 M in THF). After 12h, the reaction was quenched with AcOH:MeOH (1 :4, 20 ml.) and partitioned between saturated aqueous NaHCO3 and CHCI3. The aqueous phase was then extracted several times with CHCI3. The combined organic fractions were concentrated and the resulting white solid (7.0 g, 74%) used without further purification: LCMS (ES) m/e 288 (M+H)+.
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