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Chemical Structure| 129228-11-1 Chemical Structure| 129228-11-1

Structure of 129228-11-1

Chemical Structure| 129228-11-1

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Product Details of [ 129228-11-1 ]

CAS No. :129228-11-1
Formula : C13H28O2
M.W : 216.36
SMILES Code : CC(C)C(COC)(COC)CCC(C)C
English Name :3,3-Bis(methoxymethyl)-2,6-dimethylheptane
MDL No. :MFCD23140371
InChI Key :BHPDSAAGSUWVMP-UHFFFAOYSA-N
Pubchem ID :10867702

Safety of [ 129228-11-1 ]

Application In Synthesis of [ 129228-11-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 129228-11-1 ]

[ 129228-11-1 ] Synthesis Path-Downstream   1~3

YieldReaction ConditionsOperation in experiment
The following examples illustrate the following ethers of the invention and methods of preparing same: ... - 2,2-diisobutyl-1,3-dibutoxypropane - 2,2-diisobutyl-1,3-ethoxypropane - 2-isopentyl,2-isopropyl-1,3-dimethoxypropane - 2,2,4-ttimethyl-1,3-dimethoxypentane ...
Diethers according to claim 2 selected from the group consisting of: ... - 2,2-dibenzyl-1,3-dimethoxypropane - 2,2-bis(cyclohexylmethyl)-1,3-dimethoxypropane - 2-isopentyl-2-isopropyl-1,3-dimethoxypropane - 2-isopropyl-2-3,7-dimethyloctyl-1,3-dimethoxypropane ...
  • 2
  • [ 129228-29-1 ]
  • [ 74-88-4 ]
  • [ 129228-11-1 ]
YieldReaction ConditionsOperation in experiment
125 g Stage #1: 2-isopropyl-2-isopentyl-1,3-propanediol With sodium hydride In tetrahydrofuran; toluene at 35℃; Stage #2: iodomethane In tetrahydrofuran; toluene at 20 - 30℃; 1.iv; 5 Step iv) In a 3 liter 3/4 necked round bottom flask with thermometer pocket, ice cooling bath and overhead stirrer, and addition funnel was added 300 ml of THF and 600 ml of toluene. The stirring was started and then the compound of Formula D obtained in step iii) (100 grams; 0.53 moles, molar ratio 1.0) was added at room temperature. Then a 50% sodium hydride (72 grams, 1.5 moles, molar ratio 2.8) was gradually added in lots while the temperature is kept below 35°C. After the addition is complete, the reaction is stirred for an additional 30 minutes. Then methyl iodide (184 grams, 1.30 moles, molar ratio 2.45) was added in two equal lots at a temperature of below 30 °C and after each top the mixture was stirred for 30 minutes. After addition, the reaction mixture was stirred for a period of between 10 and 12 hours at room temperature. In order to check the progress of the reaction, small aliquots (2-3 ml) of the reaction mixture were tested for conversion by adding 0.5 ml of methanol and 5 ml of water and then diluting with 5- 10 ml of toluene. The toluene was then checked with GC wherein the monomethyl peak should be absent. Additional methyl iodide may be added if the reaction does not go to completion. When the reaction is complete methanol (25 ml) was added gradually at a temperature of 40 °C. Then water (200 ml) was gradually added at a temperature of below 40 °C. The resulting mixture is stirred for 15 minutes and separated into layers in a separating funnel. The organic layer was washed with water (100 ml) and then the organic layer evaporated by rotary evaporation to yield 125 grams of crude product having a purity > 95 %. This final product Formula 1 may be further purified by (vacuum) distillation.
  • 3
  • [ CAS Unavailable ]
  • [ 129228-29-1 ]
  • [ 129228-11-1 ]
YieldReaction ConditionsOperation in experiment
68 g With sodium hydride In tetrahydrofuran; mineral oil at 20 - 40℃; Inert atmosphere; 1.C Step C, as shown in equation 3, under argon protection, weigh 30g of sodium hydride containing 60% mineral oil by mass, place it in a 1.0L dry reaction flask, add tetrahydrofuran to dilute the sodium hydride to make The sodium hydride-tetrahydrofuran suspension with the sodium hydride mass concentration of 20-30%, then the diol solution obtained in step B is added dropwise to the sodium hydride suspension to carry out etherification reaction, and the diol solution is dripped during the dropwise addition. Add compound e methyl chloride gas, control the temperature of etherification reaction at 20-40 , until the diol solution is added dropwise to obtain the reaction mixture 3 containing product compound f; The reaction mixture 3 is filtered and separated to obtain The solid was washed 2-3 times with n-hexane, the n-hexane washing liquid was collected, the n-hexane washing liquid was mixed with the liquid phase separated by filtration, concentrated and distilled to obtain 68g containing compound f isopropyl-2-isoamyl-1, 3-dimethoxypropane solution.
 

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[ 129228-11-1 ]

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