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Product Details of [ 13025-99-5 ]

CAS No. :13025-99-5 MDL No. :N/A
Formula : C12H10N4O Boiling Point : -
Linear Structure Formula :- InChI Key :RVAFAIOWXGOYMP-OQLLNIDSSA-N
M.W : 226.23 Pubchem ID :5469567
Synonyms :

Safety of [ 13025-99-5 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 13025-99-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13025-99-5 ]

[ 13025-99-5 ] Synthesis Path-Downstream   1~50

  • 1
  • [ 872-85-5 ]
  • [ 54-85-3 ]
  • [ 13025-99-5 ]
YieldReaction ConditionsOperation in experiment
96% With hydrogenchloride In ethanol Microwave irradiation; 4.2.1.2 Microwave irradiation (MWI) General procedure: 3-Pyridinecarboxaldehyde (1) and/or 4-pyridinecarboxaldehyde (2) (1mmol), 43 ethanol (5mL), isonicotinic acid hydrazide (44 3) (1mmol) and few drops of 45 hydrochloric acid were placed in closed 46 borosilicate glass vessel fitted with a silicone cap and exposed to irradiation for 2-3min using a microwave reactor. The reaction was processed as described in the conventional procedure outlined earlier to give the same targets 47 4 and/or 5.
92% With hydrogenchloride In ethanol for 1h; Reflux; 2 Synthesis of N'-(pyridinylmethylene)isonicotino hydrazide derivatives 2 and/or 3 General procedure: To a mixture of isonicotinic acid hydrazide (1) (1 mmol) in ethanol(25 ml) was added 4-pyridinecarboxaldehyde and/or 3-pyridinecarboxaldehyde (1.2 mmol) and few drops of hydrochloricacid, then the mixture was refluxed for 1 h. After cooling, the excessof solvent was removed under reduced pressure. The product formed was recrystallized from ethanol to furnish the desired compounds.3.1.2 (E)-N'-(Pyridin-4-ylmethylene)isonicotinohydrazide (2) It was obtained as yellow crystals in 92% yield; mp: 223-224 °C (Lit. mp: 224-225 °C) [ 41 ]. 1H NMR (400 MHz, DMSO-d6): δH = 7.57 (d, 0.25H, J = 4 Hz, Ar-H), 7.71 (d, 0.25H, J = 4 Hz, Ar-H), 7.82 (d, 1.75H, J = 8 Hz, Ar-H), 7.90 (dd, 1.75H, J = 4 Hz, 8 Hz, Ar-H), 8.14 (s, 0.2H, H-C=N), 8.55 (s, 0.8H, H-C=N), 8.66 (d, 0.25H, J = 4 Hz, Ar-H), 8.74 (d, 1.75H, J = 4 Hz, Ar-H), 8.79 (d, 0.25H, J = 4 Hz, Ar-H), 8.84 (dd, 1.75H, J = 4 Hz, 8 Hz, Ar-H), 12.47 (s, 0.2H, CONH), 12.58 (s, 0.8H, CONH). 13C NMR (100 MHz, DMSO-d6): δC = 121.32, 121.62, 121.76, 123.28, 140.14, 142.58, 146.21, 149.21, 149.48, 150.38 (Ar-C), 162.08, 162.10 (C=N, C=O). HRMS (ESI) m/z = 226.1414 [M+].
90% With hydrogenchloride In ethanol at 20℃; for 0.5h;
90% In ethanol for 6h; Heating;
83% In ethanol at 100℃; General procedure: The dried hydrazide and the corresponding aldehyde (1eq) were dissolved in EtOH and refluxed at 100°C for 3-4h, then cooled to room temperature and the crystals precipitated, which are filtered and dried to obtain the final products (1-15).
With water
With acetic acid In ethanol
In methanol at 20℃; for 24h;

Reference: [1]Rezki, Nadjet; Al-Sodies, Salsabeel A.; Ahmed, Hany E.A.; Ihmaid, Saleh; Messali, Mouslim; Ahmed, Sahar; Aouad, Mohamed Reda [Journal of Molecular Liquids, 2019, vol. 284, p. 431 - 444]
[2]Rezki, Nadjet; Messali, Mouslim; Al-Sodies, Salsabeel A.; Naqvi, Arshi; Bardaweel, Sanaa K.; Al-blewi, Fawzia F.; Aouad, Mohamed R.; El Ashry, El Sayed H. [Journal of Molecular Liquids, 2018, vol. 265, p. 428 - 441]
[3]Lima, Patricia C.; Lima, Lidia M.; Da Silva, Kelli Cristine M.; Leda, Paulo Henrique O.; De Miranda, Ana Luisa P.; Fraga, Carlos A. M.; Barreiro, Eliezer J. [European Journal of Medicinal Chemistry, 2000, vol. 35, # 2, p. 187 - 203]
[4]Ni, Wen-Xiu; Li, Mian; Zhou, Xiao-Ping; Li, Zhen; Huang, Xiao-Chun; Li, Dan [Chemical Communications, 2007, # 33, p. 3479 - 3481]
[5]Gao, Han; Li, Jia-Qi; Kang, Peng-Wei; Chigan, Jia-Zhu; Wang, Huan; Liu, Lu; Xu, Yin-Sui; Zhai, Le; Yang, Ke-Wu [Bioorganic Chemistry, 2021, vol. 114]
[6]Libman; Slack [Journal of the Chemical Society, 1956, p. 2253,2257] Kakimoto; Yamamoto [Yakugaku Zasshi/Journal of the Pharmaceutical Society of Japan, 1954, vol. 74, p. 997][Chem.Abstr., 1955, p. 11650] Beyerman et al. [Recueil des Travaux Chimiques des Pays-Bas, 1954, vol. 73, p. 109,115]
[7]Channar, Pervaiz Ali; Shah, Syed Jawad Ali; Hassan, Sidra; Nisa, Zaib un; Lecka, Joanna; Sévigny, Jean; Bajorath, Jürgen; Saeed, Aamer; Iqbal, Jamshed [Chemical Biology and Drug Design, 2017, vol. 89, # 3, p. 365 - 370]
[8]Hu, Yong; Li, Jin; Zhou, Yu; Shi, Jie; Li, Guopeng; Song, Hang; Yang, Yang; Shi, Jia; Hong, Wenjing [Angewandte Chemie - International Edition, 2021, vol. 60, # 38, p. 20872 - 20878][Angew. Chem., 2021, vol. 133, # 38, p. 21040 - 21046]
  • 2
  • [ 67-56-1 ]
  • [ 13025-99-5 ]
  • [ 7774-29-0 ]
  • C12H10N4O*Hg(2+)*2I(1-)*3CH4O [ No CAS ]
YieldReaction ConditionsOperation in experiment
70% at 60℃; Sealed tube; Synthesis of [Hg(L1)I2] (1), [Hg(L2)2I2] (2) and [Hg(μ-L3)I2]n (3) 2-pyridine piconyl hydrazone (L1) (0.181 g, 0.5 mmol) and mercury(II) iodide (0.254 g, 0.5 mmol) were transferred to the main arm of a branched tube, with subsequent addition of methanol to fill the arms. The tube was sealed and immersed in an oil bath temperature controlled at 60 °C while keeping the branched arm at ambient temperature. After 24 h, crystals of 1 forming on surface of the cooler arm were removed by filtration, further purified by washing with acetone and ether, and ultimately dried in air. Crystals of 2 and 3 were prepared by combining appropriate ligand with mercury(II) iodide, following the same procedure as for 1.
  • 3
  • [ 13025-99-5 ]
  • [ 10312-55-7 ]
  • [ 5970-45-6 ]
  • [Zn(2-aminoterephthalato)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)*H<SUB>2</SUB>O]<SUB>n</SUB> [ No CAS ]
YieldReaction ConditionsOperation in experiment
83% for 0.416667h; Milling; Green chemistry;
for 0.416667h;
  • 4
  • [ 13025-99-5 ]
  • [ 10312-55-7 ]
  • [ 5743-04-4 ]
  • C8H5NO4(2-)*C12H10N4O*Cd(2+)*2H2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
for 0.416667h;
  • 5
  • zinc perchlorate [ No CAS ]
  • [ 13025-99-5 ]
  • [ 10312-55-7 ]
  • [Zn(2-aminoterephthalato)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)*H<SUB>2</SUB>O]<SUB>n</SUB> [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% With potassium hydroxide In ethanol; water
  • 6
  • cadmium(II) perchlorate hydrate [ No CAS ]
  • [ 13025-99-5 ]
  • [ 10312-55-7 ]
  • C8H5NO4(2-)*C12H10N4O*Cd(2+)*2H2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
78% With potassium hydroxide In ethanol; water
  • 7
  • zinc(II) nitrate hexahydrate [ No CAS ]
  • [ 13025-99-5 ]
  • [ 10312-55-7 ]
  • [Zn(2-aminoterephthalato)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)*H<SUB>2</SUB>O]<SUB>n</SUB> [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium hydroxide In methanol; water at 110℃; for 6h;
  • 8
  • cadmium(II) nitrate tetrhydrate [ No CAS ]
  • [ 13025-99-5 ]
  • [ 10312-55-7 ]
  • C8H5NO4(2-)*C12H10N4O*Cd(2+)*2H2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium hydroxide In methanol; water at 110℃; for 6h;
  • 9
  • [ 13025-99-5 ]
  • 1-(2-(4-methoxyphenyl)-2-oxoethyl)-4-((2-(1-(2-(4-methoxyphenyl-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl))pyridin-1-ium hexafluorophosphate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: potassium hexafluorophosphate / acetonitrile / 16 h / Reflux
  • 10
  • [ 13025-99-5 ]
  • 1-(2-(4-methoxyphenyl)-2-oxoethyl)-4-((2-(1-(2-(4-methoxyphenyl-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl))pyridin-1-ium tetrafluoroborate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: acetonitrile / 16 h / Reflux
  • 11
  • [ 13025-99-5 ]
  • 1-(2-(4-methoxyphenyl)-2-oxoethyl)-4-((2-(1-(2-(4-methoxyphenyl-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl))pyridin-1-ium trifluoroacetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: acetonitrile / 16 h / Reflux
  • 12
  • [ 13025-99-5 ]
  • 1-(2-(4-chlorophenyl)-2-oxoethyl)-4-((2-(1-(2-(4-chloro phenyl)-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium hexafluorophosphate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: potassium hexafluorophosphate / acetonitrile / 16 h / Reflux
  • 13
  • [ 13025-99-5 ]
  • 1-(2-(4-chlorophenyl)-2-oxoethyl)-4-((2-(1-(2-(4-chlorophenyl)-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium tetrafluoroborate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: acetonitrile / 16 h / Reflux
  • 14
  • [ 13025-99-5 ]
  • 1-(2-(4-chlorophenyl)-2-oxoethyl)-4-((2-(1-(2-(4-chlorophenyl)-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium trifluoroacetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: acetonitrile / 16 h / Reflux
  • 15
  • [ 13025-99-5 ]
  • 1-(2-(4-nitrophenyl)-2-oxoethyl)-4-((2-(1-(2-(4-nitro phenyl)-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium hexafluorophosphate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: potassium hexafluorophosphate / acetonitrile / 16 h / Reflux
  • 16
  • [ 13025-99-5 ]
  • 1-(2-(4-nitrophenyl)-2-oxoethyl)-4-((2-(1-(2-(4-nitrophenyl)-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium tetrafluoroborate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: acetonitrile / 16 h / Reflux
  • 17
  • [ 13025-99-5 ]
  • 1-(2-(4-nitrophenyl)-2-oxoethyl)-4-((2-(1-(2-(4-nitrophenyl)-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium trifluoroacetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / Reflux 2: acetonitrile / 16 h / Reflux
  • 18
  • [ 13025-99-5 ]
  • [ 2632-13-5 ]
  • 1-(2-(4-methoxyphenyl)-2-oxoethyl)-4-((2-(1-(2-(4-methoxyphenyl-2-oxoethyl)pyridin-1-ium-4‑carbonyl) hydrazono)methyl))pyridin-1-ium bromide [ No CAS ]
YieldReaction ConditionsOperation in experiment
88% In acetonitrile Reflux; 1 General procedures for the synthesis of dipyridinium ionic liquids tethered hydrazones 4-9 General procedure: A mixture of compound 2 and/or 3 (1mmol) in acetonitrile (30ml) and the appropriate phenacyl bromide (2.1mmol) was refluxed for 6-12h. The solvent was reduced by evaporation under reduce pressure, the precipitate formed was collected by filtration and/or extraction by chloroform to afford the desired dicationic liquids 4-9. 3.2.1 1-(2-(4-Methoxyphenyl)-2-oxoethyl)-4-((2-(1-(2-(4-methoxyphenyl-2-oxoethyl)pyridin-1-ium-4-carbonyl) hydrazono) methyl)pyridin-1-ium bromide (4) It was obtained as syrup in 88% yield. 1H NMR (400 MHz, DMSO-d6): δH = 3.92 (s, 6H 2 * OCH3), 6.58 (d, 4H, J = 8 Hz, 2 * NCH2), 7.22 (d, 4H, J = 8 Hz, Ar-H), 8.09 (d, 4H, J = 8 Hz, Ar-H), 8.29 (d, 0.5H, J = 4 Hz, Ar-H), 8.40 (d, 0.5H, J = 4 Hz, Ar-H), 8.52 (s, 0.25H, H-C=N), 8.57 (d, 1.5H, J = 8 Hz, Ar-H), 8.71 (d, 1.5H, J = 4 Hz, Ar-H), 8.78 (s, 0.75H, H-C=N), 8.97 (d, 0.5H, J = 4 Hz, Ar-H), 9.07 (d, 1.5H, J = 8 Hz, Ar-H), 9.19 (d, 0.5H, J = 4 Hz, Ar-H), 9.28 (d, 1.5H, J = 4 Hz, Ar-H), 13.37 (s, 0.25H, CONH), 13.42 (s, 0.75H, CONH). 13C NMR (100 MHz, DMSO-d6): δC = 56.32 (2 * OCH3), 66.12; 66.76 (2 * NCH2), 141.92; 125.13; 126.75; 127.56; 131.25; 131.30; 145.04; 147.23; 147.76; 147.89; 149.83 (Ar-C), 160.54; 164.79 (C=N, C=O), 189.08; 189.46 (2 * CH2C=O). HRMS (ESI) m/z = 684.3530 [M+].
  • 19
  • [ 13025-99-5 ]
  • [ 536-38-9 ]
  • 1-(2-(4-chlorophenyl)-2-oxoethyl)-4-((2-(1-(2-(4-chlorophenyl)-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazone)methyl)pyridin-1-ium bromide [ No CAS ]
YieldReaction ConditionsOperation in experiment
90% In acetonitrile Reflux; 2 General procedures for the synthesis of dipyridinium ionic liquids tethered hydrazones 4-9 General procedure: A mixture of compound 2 and/or 3 (1mmol) in acetonitrile (30ml) and the appropriate phenacyl bromide (2.1mmol) was refluxed for 6-12h. The solvent was reduced by evaporation under reduce pressure, the precipitate formed was collected by filtration and/or extraction by chloroform to afford the desired dicationic liquids 4-9.
  • 20
  • [ 13025-99-5 ]
  • [ 99-81-0 ]
  • 1-(2-(4-nitrophenyl)-2-oxoethyl)-4-((2-(1-(2-(4-nitrophenyl)-2-oxoethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium bromide [ No CAS ]
YieldReaction ConditionsOperation in experiment
90% In acetonitrile Reflux; 3 General procedures for the synthesis of dipyridinium ionic liquids tethered hydrazones 4-9 General procedure: A mixture of compound 2 and/or 3 (1mmol) in acetonitrile (30ml) and the appropriate phenacyl bromide (2.1mmol) was refluxed for 6-12h. The solvent was reduced by evaporation under reduce pressure, the precipitate formed was collected by filtration and/or extraction by chloroform to afford the desired dicationic liquids 4-9.
  • 21
  • zinc(II) nitrate hexahydrate [ No CAS ]
  • [ 13025-99-5 ]
  • [ 10312-55-7 ]
  • [ 7732-18-5 ]
  • [Zn(2-aminoterephthalato)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)*H<SUB>2</SUB>O]<SUB>n</SUB> [ No CAS ]
YieldReaction ConditionsOperation in experiment
88% With potassium hydroxide In methanol at 110℃; for 6h;
  • 22
  • [ 13025-99-5 ]
  • cyclohexane-1,4-dicarboxylic acid [ No CAS ]
  • [ 5970-45-6 ]
  • [Zn(1,4-cyclohexanedicarboxylate)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)]*H2O}n [ No CAS ]
YieldReaction ConditionsOperation in experiment
for 0.416667h;
  • 23
  • [ 13025-99-5 ]
  • cyclohexane-1,4-dicarboxylic acid [ No CAS ]
  • [ 5743-04-4 ]
  • [Cd(1,4-cyclohexanedicarboxylate)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)]*H2O}n [ No CAS ]
YieldReaction ConditionsOperation in experiment
for 0.416667h;
  • 24
  • zinc perchlorate [ No CAS ]
  • [ 13025-99-5 ]
  • cyclohexane-1,4-dicarboxylic acid [ No CAS ]
  • [ 7732-18-5 ]
  • [Zn(1,4-cyclohexanedicarboxylate)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)]*H2O}n [ No CAS ]
YieldReaction ConditionsOperation in experiment
74% In methanol at 20℃;
  • 25
  • cadmium(II) perchlorate hexahydrate [ No CAS ]
  • [ 13025-99-5 ]
  • cyclohexane-1,4-dicarboxylic acid [ No CAS ]
  • [ 7732-18-5 ]
  • [Cd(1,4-cyclohexanedicarboxylate)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)]*H2O}n [ No CAS ]
YieldReaction ConditionsOperation in experiment
75% In methanol at 20℃;
  • 26
  • zinc(II) nitrate hexahydrate [ No CAS ]
  • [ 13025-99-5 ]
  • cyclohexane-1,4-dicarboxylic acid [ No CAS ]
  • [Zn(1,4-cyclohexanedicarboxylate)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)]*H2O}n [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium hydroxide In methanol; water at 100℃; for 6h; Reflux;
  • 27
  • cadmium(II) nitrate tetrhydrate [ No CAS ]
  • [ 13025-99-5 ]
  • cyclohexane-1,4-dicarboxylic acid [ No CAS ]
  • [Cd(1,4-cyclohexanedicarboxylate)((E)-N'-(pyridin-4-ylmethylene)isonicotinohydrazide)]*H2O}n [ No CAS ]
YieldReaction ConditionsOperation in experiment
With potassium hydroxide In methanol at 100℃; for 6h; Reflux;
  • 28
  • [ 13025-99-5 ]
  • [ 589-10-6 ]
  • 1-(2-phenoxyethyl)-4-((2-(1-(2-phenoxyethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium bromide [ No CAS ]
YieldReaction ConditionsOperation in experiment
94% In acetonitrile for 0.05h; Microwave irradiation; 4.1 4.2.3.2 Microwave irradiation (MWI) General procedure: Dipyridine Schiff base 4 and/or 5 (1mmol), acetonitrile (5mL), and the appropriate bromoalkoxybenzene derivatives (2mmol) were placed in closed borosilicate glass vessel fitted with a silicone cap and exposed to irradiation for 3-4min using a microwave reactor. The reaction was processed as described in the conventional procedure outlined earlier to give the same dicationic pyridinium bromides 6-11.
  • 29
  • [ 13025-99-5 ]
  • [ 588-63-6 ]
  • 1-(3-phenoxypropyl)-4-((2-(1-(3-phenoxypropyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium bromide [ No CAS ]
YieldReaction ConditionsOperation in experiment
96% In acetonitrile for 0.05h; Microwave irradiation; 4.2 4.2.3.2 Microwave irradiation (MWI) General procedure: Dipyridine Schiff base 4 and/or 5 (1mmol), acetonitrile (5mL), and the appropriate bromoalkoxybenzene derivatives (2mmol) were placed in closed borosilicate glass vessel fitted with a silicone cap and exposed to irradiation for 3-4min using a microwave reactor. The reaction was processed as described in the conventional procedure outlined earlier to give the same dicationic pyridinium bromides 6-11.
  • 30
  • [ 13025-99-5 ]
  • [ 1200-03-9 ]
  • 1-(4-phenoxybutyl)-4-((2-(1-(4-phenoxybutyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium bromide [ No CAS ]
YieldReaction ConditionsOperation in experiment
96% In acetonitrile for 0.0666667h; Microwave irradiation; 4.3 4.2.3.2 Microwave irradiation (MWI) General procedure: Dipyridine Schiff base 4 and/or 5 (1mmol), acetonitrile (5mL), and the appropriate bromoalkoxybenzene derivatives (2mmol) were placed in closed borosilicate glass vessel fitted with a silicone cap and exposed to irradiation for 3-4min using a microwave reactor. The reaction was processed as described in the conventional procedure outlined earlier to give the same dicationic pyridinium bromides 6-11.
  • 31
  • [ 13025-99-5 ]
  • 1-(4-phenoxybutyl)-4-((2-(1-(4-phenoxybutyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium trifluoroacetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.07 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 32
  • [ 13025-99-5 ]
  • 1-(4-phenoxybutyl)-4-((2-(1-(4-phenoxybutyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium thiocyanate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.07 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 33
  • [ 13025-99-5 ]
  • 1-(4-phenoxybutyl)-4-((2-(1-(4-phenoxybutyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium dicyanamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.07 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 34
  • [ 13025-99-5 ]
  • 1-(2-phenoxyethyl)-4-((2-(1-(2-phenoxyethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium hexafluorophosphate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: potassium hexafluorophosphate / acetonitrile / 0.17 h / Microwave irradiation
  • 35
  • [ 13025-99-5 ]
  • 1-(2-phenoxyethyl)-4-((2-(1-(2-phenoxyethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium tetrafluoroborate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 36
  • [ 13025-99-5 ]
  • 1-(2-phenoxyethyl)-4-((2-(1-(2-phenoxyethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium trifluoroacetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 37
  • [ 13025-99-5 ]
  • 1-(2-phenoxyethyl)-4-((2-(1-(2-phenoxyethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium thiocyanate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 38
  • [ 13025-99-5 ]
  • 1-(2-phenoxyethyl)-4-((2-(1-(2-phenoxyethyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium dicyanamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 39
  • [ 13025-99-5 ]
  • 1-(3-phenoxypropyl)-4-((2-(1-(3-phenoxypropyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium hexafluorophosphate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: potassium hexafluorophosphate / acetonitrile / 0.17 h / Microwave irradiation
  • 40
  • [ 13025-99-5 ]
  • 1-(3-phenoxypropyl)-4-((2-(1-(3-phenoxypropyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium tetrafluoroborate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 41
  • [ 13025-99-5 ]
  • 1-(3-phenoxypropyl)-4-((2-(1-(3-phenoxypropyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium trifluoroacetate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 42
  • [ 13025-99-5 ]
  • 1-(3-phenoxypropyl)-4-((2-(1-(3-phenoxypropyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium thiocyanate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 43
  • [ 13025-99-5 ]
  • 1-(3-phenoxypropyl)-4-((2-(1-(3-phenoxypropyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium dicyanamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.05 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 44
  • [ 13025-99-5 ]
  • 1-(4-phenoxybutyl)-4-((2-(1-(4-phenoxybutyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium hexafluorophosphate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.07 h / Microwave irradiation 2: potassium hexafluorophosphate / acetonitrile / 0.17 h / Microwave irradiation
  • 45
  • [ 13025-99-5 ]
  • 1-(4-phenoxybutyl)-4-((2-(1-(4-phenoxybutyl)pyridin-1-ium-4‑carbonyl)hydrazono)methyl)pyridin-1-ium tetrafluoroborate [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: acetonitrile / 0.07 h / Microwave irradiation 2: acetonitrile / 0.17 h / Microwave irradiation
  • 46
  • [ 67-56-1 ]
  • cobalt(II) nitrate hexahydrate [ No CAS ]
  • [ 13025-99-5 ]
  • [ 2215-89-6 ]
  • [ 7732-18-5 ]
  • [ 33513-42-7 ]
  • Co(2+)*C14H8O5(2-)*C12H10N4O*2C3H7NO*3CH4O*2H2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
68% In ethanol at 90℃; for 72h; Autoclave;
  • 47
  • [ 67-56-1 ]
  • [ 13025-99-5 ]
  • [ 100-21-0 ]
  • cobalt(II) perchlorate hexahydrate [ No CAS ]
  • (x)CH4O*C8H4O4(2-)*C12H10N4O*Co(2+)*2H2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
79% Stage #1: methanol; (E)-N′-(pyridin-4-ylmethylene) isonicotinohydrazide; terephthalic acid With sodium hydroxide for 0.25h; Stage #2: cobalt(II) perchlorate hexahydrate In water at 20℃; Sealed tube;
  • 48
  • [ 67-56-1 ]
  • cobalt(II) nitrate hexahydrate [ No CAS ]
  • [ 13025-99-5 ]
  • [ 100-21-0 ]
  • (x)CH4O*C8H4O4(2-)*C12H10N4O*Co(2+)*2H2O [ No CAS ]
YieldReaction ConditionsOperation in experiment
92% With sodium hydroxide In ethanol; water at 20℃; for 8h;
  • 49
  • [ 55-22-1 ]
  • [ 13025-99-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: sulfuric acid / 2 h / 85 - 95 °C 2: hydrazine hydrate / ethanol / 80 °C 3: ethanol / 100 °C
  • 50
  • [ 2459-09-8 ]
  • [ 13025-99-5 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: hydrazine hydrate / ethanol / 80 °C 2: ethanol / 100 °C
Same Skeleton Products
Historical Records

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Related Parent Nucleus of
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Pyridines

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