Home Cart 0 Sign in  

[ CAS No. 1315350-04-9 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 1315350-04-9
Chemical Structure| 1315350-04-9
Structure of 1315350-04-9 *Storage: {[proInfo.prStorage]}

Quality Control of [ 1315350-04-9 ]

Related Doc. of [ 1315350-04-9 ]

SDS
Alternatived Products of [ 1315350-04-9 ]
Alternatived Products of [ 1315350-04-9 ]

Product Details of [ 1315350-04-9 ]

CAS No. :1315350-04-9MDL No. :
Formula : C13H17BN2O2 Boiling Point : -
Linear Structure Formula :-InChI Key :-
M.W :244.10Pubchem ID :-
Synonyms :

Computed Properties of [ 1315350-04-9 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 1315350-04-9 ]

Signal Word:WarningClass:
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501UN#:
Hazard Statements:H302-H312-H315-H319-H332-H335Packing Group:
GHS Pictogram:

Application In Synthesis of [ 1315350-04-9 ]

  • Downstream synthetic route of [ 1315350-04-9 ]

[ 1315350-04-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1315350-04-9 ]
  • [ 57486-69-8 ]
  • [ 1434044-06-0 ]
YieldReaction ConditionsOperation in experiment
89% General procedure: To a 2-5 mL capacity microwave vial was charged <strong>[57486-69-8]methyl 2-(2-bromophenyl)acetate</strong> (0.100g, 0.43 mmol), 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (0.115 g, 0.523 mmol)and cesium carbonate (0.280 g, 0.86 mmol) in anhydrous 1,2-dimethoxy ethane (4 mL). Themixture was stirred and degassed with argon for 5 min. To this mixture was added Pd(PPh3)4(25 mg, 0.021 mmol) under argon atmosphere, and purged for 2 min. The tube was sealedand irradiated in microwave at 125 C for 0.5 h (This is the internal temperature of reactionmixture and monitored on the screen through a sensor). The vial was cooled to 0C over aperiod of 15 min, followed by addition of 1M potassium tert-butoxide (0.65 mL, 0.65 mmol)solution in THF. The resulting mixture was stirred for 10 minutes and quenched withsaturated ammonium chloride solution. The mixture was diluted with ethyl acetate (30 mL)and washed with water and brine. The organic layer was dried over anhydrous sodiumsulfate, filtered and concentrated. The residue obtained was purified by flash columnchromatography by eluting with gradient of 2-20% ethyl acetate in hexane to afford the 5Hdibenzo[b,d]azepin-6(7H)-one (4) as off white solid (0.075 g, 82%).
Historical Records

Related Functional Groups of
[ 1315350-04-9 ]

Nitriles

Chemical Structure| 1352575-06-4

[ 1352575-06-4 ]

2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.94

Organoboron

Chemical Structure| 1352575-06-4

[ 1352575-06-4 ]

2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.94

Chemical Structure| 1352575-06-4

[ 1352575-06-4 ]

2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.94

Chemical Structure| 948592-80-1

[ 948592-80-1 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Similarity: 0.93

Chemical Structure| 948592-80-1

[ 948592-80-1 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Similarity: 0.93

Chemical Structure| 1036991-35-1

[ 1036991-35-1 ]

3-Amino-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.92

Amines

Chemical Structure| 1352575-06-4

[ 1352575-06-4 ]

2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.94

Chemical Structure| 948592-80-1

[ 948592-80-1 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Similarity: 0.93

Chemical Structure| 863578-36-3

[ 863578-36-3 ]

5-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Similarity: 0.90

Aryls

Chemical Structure| 1352575-06-4

[ 1352575-06-4 ]

2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.94

Chemical Structure| 948592-80-1

[ 948592-80-1 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Similarity: 0.93

Organoboron

Chemical Structure| 1352575-06-4

[ 1352575-06-4 ]

2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.94

Chemical Structure| 1352575-06-4

[ 1352575-06-4 ]

2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.94

Chemical Structure| 948592-80-1

[ 948592-80-1 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Similarity: 0.93

Chemical Structure| 948592-80-1

[ 948592-80-1 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Similarity: 0.93

Chemical Structure| 1036991-35-1

[ 1036991-35-1 ]

3-Amino-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.92

Esters

Chemical Structure| 1384855-68-8

[ 1384855-68-8 ]

3-Amino-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.97

Chemical Structure|

[ ]

3,4-DIamino-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.95

Chemical Structure|

[ ]

3-Amino-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile, HCl

Similarity: 0.95

Chemical Structure| 1352575-06-4

[ 1352575-06-4 ]

2-Amino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile

Similarity: 0.94

Chemical Structure| 948592-80-1

[ 948592-80-1 ]

4-Methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

Similarity: 0.93