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Chemical Structure| 1333377-65-3 Chemical Structure| 1333377-65-3

Structure of CHR-6494
CAS No.: 1333377-65-3

Chemical Structure| 1333377-65-3

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CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation.

Synonyms: CHR-6494

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Product Details of CHR-6494

CAS No. :1333377-65-3
Formula : C16H16N6
M.W : 292.34
SMILES Code : CCCNC1=NN2C(C=C1)=NC=C2C3=CC4=C(NN=C4)C=C3
Synonyms :
CHR-6494
MDL No. :MFCD22666352
InChI Key :CZZCAOGIEGXMBZ-UHFFFAOYSA-N
Pubchem ID :70679308

Safety of CHR-6494

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Isoform Comparison

Biological Activity

Description
CHR-6494 is a potent inhibitor of haspin, with an IC50 of 2 nM. CHR-6494 inhibits histone H3T3 phosphorylation. CHR-6494 can be used in the research of cancer[1].

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Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

3.42mL

0.68mL

0.34mL

17.10mL

3.42mL

1.71mL

34.21mL

6.84mL

3.42mL

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