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Chemical Structure| 1354545-57-5 Chemical Structure| 1354545-57-5

Structure of CEP-28122 mesylate HCl
CAS No.: 1354545-57-5

Chemical Structure| 1354545-57-5

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CEP-28122 mesylate hydrochloride is a diaminopyrimidine derivative with high efficiency, selectivity, and oral activity, serving as an ALK inhibitor with an IC50 of 1.9 nM and exhibiting antitumor properties along with good pharmacokinetic characteristics.

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Product Details of CEP-28122 mesylate HCl

CAS No. :1354545-57-5
Formula : C29H40Cl2N6O6S
M.W : 671.64
SMILES Code : [H]Cl.O=C(N)[C@H]1[C@@]2([H])C[C@@]([H])([C@H]1NC3=NC(NC4=CC=C5C(CC[C@H](CC5)N6CCOCC6)=C4OC)=NC=C3Cl)C=C2.CS(=O)(O)=O
MDL No. :N/A

Safety of CEP-28122 mesylate HCl

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Related Pathways of CEP-28122 mesylate HCl

RTK

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Biological Activity

Description
CEP-28122 mesylate hydrochloride, a derivative of diaminopyrimidine, is a powerful, selective, and orally available ALK inhibitor that demonstrates an IC50 of 1.9 nM, showcasing antitumor efficacy and favorable pharmacokinetic properties[1].

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