Home Cart 0 Sign in  

[ CAS No. 135643-82-2 ]

{[proInfo.proName]} ,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 135643-82-2
Chemical Structure| 135643-82-2
Structure of 135643-82-2 *Storage: {[proInfo.prStorage]}

Quality Control of [ 135643-82-2 ]

Related Doc. of [ 135643-82-2 ]

SDS
Alternatived Products of [ 135643-82-2 ]
Alternatived Products of [ 135643-82-2 ]

Product Details of [ 135643-82-2 ]

CAS No. :135643-82-2MDL No. :N/A
Formula : C8H14O4 Boiling Point : -
Linear Structure Formula :-InChI Key :N/A
M.W :174.19Pubchem ID :10954008
Synonyms :

Computed Properties of [ 135643-82-2 ]

TPSA : 44.8 H-Bond Acceptor Count : 4
XLogP3 : 0.9 H-Bond Donor Count : 0
SP3 : 0.88 Rotatable Bond Count : 4

Safety of [ 135643-82-2 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P261-P305+P351+P338UN#:N/A
Hazard Statements:H302-H315-H319-H335Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 135643-82-2 ]

  • Downstream synthetic route of [ 135643-82-2 ]

[ 135643-82-2 ] Synthesis Path-Downstream   1~7

  • 1
  • [ 521-18-6 ]
  • [ 135643-82-2 ]
  • [ 141507-29-1 ]
YieldReaction ConditionsOperation in experiment
96% With hydrogenchloride; In N-methyl-acetamide; methanol; A. Under nitrogen with stirring at room temperature solution of 17beta-hydroxy-5alpha-androstan-3-one (the compound of Formula VII wherein X-Y is STR14 and Z is H, 145.2 g.) in dry dimethylformamide (500 ml.) was added slowly to a suspension of sodium hydride (60%, 48 g.) in dry dimethylformamide (100 ml.). A solution of <strong>[135643-82-2]methyl glycolate tetrahydropyranyl ether</strong> (130.5 g.) in dry dimethylformamide (100 ml.) was then slowly added. After continued stirring overnight methanol (50 ml.) was added slowly. The resulting mixture was poured into ice-water (4 1.). The resulting solution was filtered and the filter pad was washed with water. Neutralization of the filtrate with hydrochloric acid (6N) gave a white crystalline solid, which was collected by filtration, washed with water and dried, affording 17beta-hydroxy-2alpha-{[(tetrahydro-2H-pyran-2-yl)oxy]acetyl}-5alpha-androstan-3-one (the compound of Formula VI wherein Q' is tetrahydropyranyl, X-Y is STR15 and Z is H; 206 g, 96% yield). Recrystallization of part (15.0 g.) of the product from cyclohexane gave a white crystalline solid (12.0 g.) having m.r. 128-131 C.
  • 2
  • [ 4011-35-2 ]
  • [ 135643-82-2 ]
  • [ 135643-90-2 ]
  • 3
  • [ 434-03-7 ]
  • [ 135643-82-2 ]
  • (1R,3aS,3bR,10aR,10bS,12aS)-1-Ethynyl-1-hydroxy-10a,12a-dimethyl-1,2,3,3a,3b,4,5,9,10,10a,10b,11,12,12a-tetradecahydro-7-oxa-dicyclopenta[a,h]phenanthren-8-one [ No CAS ]
  • 4
  • [ 434-22-0 ]
  • [ 135643-82-2 ]
  • (1S,3aS,3bR,10aR,10bS,12aS)-1-Hydroxy-12a-methyl-1,2,3,3a,3b,4,5,9,10,10a,10b,11,12,12a-tetradecahydro-7-oxa-dicyclopenta[a,h]phenanthren-8-one [ No CAS ]
  • 6
  • [ 925-90-6 ]
  • [ 135643-82-2 ]
  • 1-((tetrahydro-2H-pyran-2-yloxy)methyl)cyclopropanol [ No CAS ]
  • 7
  • [ 1823-14-9 ]
  • [ 135643-82-2 ]
  • 7-phenyl-1-(tetrahydro-pyran-2-yloxy)-hept-3-yn-2-one [ No CAS ]
Historical Records

Related Functional Groups of
[ 135643-82-2 ]

Esters

Chemical Structure| 61675-94-3

[ 61675-94-3 ]

Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate

Similarity: 0.97

Chemical Structure| 83-87-4

[ 83-87-4 ]

(3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Similarity: 0.72

Chemical Structure| 6065-82-3

[ 6065-82-3 ]

Ethyl diethoxyacetate

Similarity: 0.71

Chemical Structure| 10495-09-7

[ 10495-09-7 ]

Ethyl 4,4-diethoxy-3-oxobutanoate

Similarity: 0.68

Chemical Structure| 78086-72-3

[ 78086-72-3 ]

(4R,5S)-Methyl 2,2,5-trimethyl-1,3-dioxolane-4-carboxylate

Similarity: 0.67

Ethers

Chemical Structure| 61675-94-3

[ 61675-94-3 ]

Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate

Similarity: 0.97

Chemical Structure| 6065-82-3

[ 6065-82-3 ]

Ethyl diethoxyacetate

Similarity: 0.71

Chemical Structure| 10495-09-7

[ 10495-09-7 ]

Ethyl 4,4-diethoxy-3-oxobutanoate

Similarity: 0.68

Chemical Structure| 89-91-8

[ 89-91-8 ]

Methyl 2,2-dimethoxyacetate

Similarity: 0.67

Chemical Structure| 10601-80-6

[ 10601-80-6 ]

Ethyl 3,3-diethoxypropionate

Similarity: 0.66

Related Parent Nucleus of
[ 135643-82-2 ]

Tetrahydropyrans

Chemical Structure| 61675-94-3

[ 61675-94-3 ]

Ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)acetate

Similarity: 0.97

Chemical Structure| 83-87-4

[ 83-87-4 ]

(3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Similarity: 0.72

Chemical Structure| 84355-44-2

[ 84355-44-2 ]

Methyl tetrahydro-2H-pyran-2-carboxylate

Similarity: 0.66

Chemical Structure| 63-42-3

[ 63-42-3 ]

(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexanal

Similarity: 0.61

Chemical Structure| 51673-83-7

[ 51673-83-7 ]

Tetrahydro-2H-pyran-2-carboxylic acid

Similarity: 0.61