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Chemical Structure| 1357248-83-9 Chemical Structure| 1357248-83-9

Structure of LIN28 inhibitor LI71
CAS No.: 1357248-83-9

Chemical Structure| 1357248-83-9

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LIN28 inhibitor LI71 is a potent and cell-permeable LIN28 inhibitor, which abolishes LIN28-mediated oligouridylation with an IC50 of 7 uM. LIN28 inhibitor LI71 directly binds the cold shock domain (CSD) to suppress LIN28’s activity against let-7 in leukemia cells and embryonic stem cells.

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Product Details of LIN28 inhibitor LI71

CAS No. :1357248-83-9
Formula : C21H21NO3
M.W : 335.40
SMILES Code : O=C(C1=CC=C(C=C1)[C@@H]2NC3=C([C@]4([C@@]2(CC=C4)[H])[H])C=CC=C3OCC)O
MDL No. :MFCD07363437
InChI Key :QWJMABCFVYELBB-GJYPPUQNSA-N
Pubchem ID :6541811

Safety of LIN28 inhibitor LI71

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Isoform Comparison

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.98mL

0.60mL

0.30mL

14.91mL

2.98mL

1.49mL

29.82mL

5.96mL

2.98mL

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