Structure of Lubiprostone
CAS No.: 136790-76-6
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The BI-3802 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.
Lubiprostone is an ClC-2 chloride channel activator used in the treatment of idiopathic chronic constipation.
Synonyms: SPI-0211; RU-0211
4.5
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Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
Search for reports by entering the product batch number.
Batch number can be found on the product's label following the word 'Batch'.
CAS No. : | 136790-76-6 |
Formula : | C20H32F2O5 |
M.W : | 390.46 |
SMILES Code : | CCCCC(F)(F)C(CC[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O)=O |
Synonyms : |
SPI-0211; RU-0211
|
MDL No. : | MFCD20268389 |
GHS Pictogram: |
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Signal Word: | Warning |
Hazard Statements: | H315-H319-H335 |
Precautionary Statements: | P261-P305+P351+P338 |
Clinical Trial:
NCT Number | Conditions | Phases | Recruitment | Completion Date | Locations |
NCT00953017 | - | Completed | - | - | |
NCT03720613 | - | Not yet recruiting | November 1, 2025 | - | |
NCT00577499 | - | Terminated(Recruitment was sub... More >>optimal) Less << | - | - | |
NCT02481947 | Chronic Idiopathic Constipatio... More >>n Less << | Phase 3 | Completed | - | - |
NCT00399542 | Irritable Bowel Syndrome ... More >> Constipation Less << | Phase 3 | Completed | - | - |
NCT01298219 | Opioid-induced Bowel Dysfuncti... More >>on Less << | Phase 3 | Completed | - | - |
NCT00399542 | - | Completed | - | - | |
NCT00380250 | Irritable Bowel Syndrome With ... More >>Constipation Less << | Phase 3 | Completed | - | - |
NCT00611442 | Bowel Preparation for Colonosc... More >>opy Less << | Not Applicable | Completed | - | United States, Texas ... More >> Brooke Army Medical Center Fort Sam Houston, Texas, United States, 78234 Less << |
NCT00611442 | - | Completed | - | - | |
NCT01372423 | Chronic Idiopathic Constipatio... More >>n Less << | Phase 3 | Completed | - | - |
NCT01162863 | Irritable Bowel Syndrome ... More >> Constipation Less << | Not Applicable | Completed | - | United States, Michigan ... More >> University of Michigan Health System Ann Arbor, Michigan, United States, 48103 Less << |
NCT00985569 | - | Withdrawn(Enrollment was never... More >> begun.) Less << | November 2010 | United States, Florida ... More >> Geriatric Medical Associates Brooksville, Florida, United States Cassellberry Family Practice Casselberry, Florida, United States Osler Geriatrics Melbourne, Florida, United States Less << | |
NCT00953017 | Colonoscopy | Phase 4 | Completed | - | United States, Texas ... More >> Brooke Army Medical Center San Antonio, Texas, United States, 78248 Less << |
NCT01993875 | Chronic Idiopathic Constipatio... More >>n Less << | Phase 3 | Completed | - | United States, Alabama ... More >> Anniston, Alabama, United States, 36207 United States, California Anaheim, California, United States, 92801 United States, Florida Deland, Florida, United States, 32720 Hollywood, Florida, United States, 33024 Orlando, Florida, United States, 32809 South Miami, Florida, United States, 33143 United States, Kansas Overland Park, Kansas, United States, 66212 United States, New Jersey Marlton, New Jersey, United States, 08053 United States, North Carolina Raleigh, North Carolina, United States, 27612 United States, Utah Salt Lake City, Utah, United States, 84106 United States, Wisconsin West Bend, Wisconsin, United States, 53095 Less << |
NCT01674530 | Chronic Idiopathic Constipatio... More >>n Less << | Phase 3 | Completed | - | - |
NCT00934479 | Other Constipation|Irritable B... More >>owel Syndrome Less << | PHASE1 | COMPLETED | 2025-02-12 | Mayo Clinic Arizona, Scottsdal... More >>e, Arizona, 85259, United States Less << |
NCT00452335 | Constipation | Phase 4 | Completed | - | United States, Arizona ... More >> Phoenix Children's Hospital Pheonix, Arizona, United States, 85016 United States, Arkansas Arkansas Pediatric Clinic Little Rock, Arkansas, United States, 72005 United States, California Children's Hospital and Research Center Oakland Oakland, California, United States, 94609 United States, Florida Nemours Children's Clinic - Jacksonville Jacksonville, Florida, United States, 32207 Nemours Children's Clinic - Pensacola Pensacola, Florida, United States, 32504 United States, Illinois Center for Children's Digestive Health Park Ridge, Illinois, United States, 60068 University of Illinois at Peoria Peoria, Illinois, United States, 61613 University of Illinois at Chicago Springfield, Illinois, United States, 62708-0787 United States, Indiana Indiana University Indianapolis, Indiana, United States, 46202 United States, Kansas University of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Massachusetts Children's Hospital Boston Boston, Massachusetts, United States, 02115 United States, Nebraska The Center for Human Nutrition, Inc. Omaha, Nebraska, United States, 68105 United States, New Jersey AHS Hospital Corporation Morristown, New Jersey, United States, 07962 United States, Ohio Children's Research Institute Columbus, Ohio, United States, 43205 Pediatric Associates of Fairfield, Inc. Fairfield, Ohio, United States, 45014 United States, Pennsylvania Regional Gastroenterology Associates of Lancaster, Ltd. Lancaster, Pennsylvania, United States, 17604 United States, Tennessee Southeastern Clinical Research Chattanooga, Tennessee, United States, 37403 Jackson Clinic Jackson, Tennessee, United States, 38305 United States, Wisconsin Medical College of Wisconsin Milwaukee, Wisconsin, United States, 53226 Less << |
NCT00452335 | - | Completed | - | - | |
NCT00595946 | Opioid-Induced Bowel Dysfuncti... More >>on Less << | Phase 3 | Completed | - | - |
NCT00595946 | - | Completed | - | - | |
NCT00597428 | Opioid-Induced Bowel Dysfuncti... More >>on Less << | Phase 3 | Completed | - | - |
NCT01460225 | Chronic Idiopathic Constipatio... More >>n Less << | Phase 4 | Completed | - | United States, New Hampshire ... More >> Dartmouth-Hitchcock Medical Center Lebanon, New Hampshire, United States, 03756 Less << |
NCT00380250 | - | Completed | - | - | |
NCT01162863 | - | Completed | - | - | |
NCT01460225 | - | Completed | - | - | |
NCT00620061 | Opioid-Induced Bowel Dysfuncti... More >>on Less << | Phase 3 | Completed | - | - |
NCT00689026 | Diabetes Mellitus, Type 1 ... More >> Diabetes Mellitus, Type 2 Less << | Not Applicable | Terminated | - | United States, Georgia ... More >> Medical College of Georgia Augusta, Georgia, United States, 30912 Less << |
NCT00662363 | Constipation | Not Applicable | Completed | - | United States, Illinois ... More >> Rehabilitation Institute of Chicago Chicago, Illinois, United States, 60302 Less << |
NCT00597428 | - | Completed | - | - | |
NCT00662363 | - | Completed | - | - | |
NCT00746395 | - | Completed | - | - | |
NCT00746395 | Inflammatory Bowel Disease | Phase 4 | Completed | - | United States, Alabama ... More >> USA Pavilion at Infirmary West Mobile, Alabama, United States, 36693 Less << |
NCT00844831 | Constipation | PHASE4 | COMPLETED | 2025-05-11 | University of Louisville, Loui... More >>sville, Kentucky, 40202, United States Less << |
NCT00689026 | - | Terminated | - | - | |
NCT02042183 | Constipation - Functional | Phase 3 | Completed | - | - |
NCT01096290 | Constipation | Phase 4 | Completed | - | United States, Alabama ... More >> USA Pavilion at Infirmary West Mobile, Alabama, United States, 36693 Less << |
NCT00669461 | Constipation|Parkinson's Disea... More >>se Less << | TERMINATED | 2025-09-10 | University of Arkansas for Med... More >>ical Sciences, Little Rock, Arkansas, 72205, United States Less << | |
NCT00706004 | Constipation ... More >>Cystic Fibrosis Less << | Not Applicable | Completed | - | United States, Arkansas ... More >> University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72205 Less << |
NCT00706004 | - | Completed | - | - | |
NCT02544152 | Irritable Bowel Syndrome | Phase 2 | Terminated | - | United States, Alabama ... More >> E Squared Research, Inc. Huntsville, Alabama, United States, 35801 United States, Arkansas Arkansas Gastroenterology North Little Rock, Arkansas, United States, 72117 United States, California GW Research Inc. Chula Vista, California, United States, 91910 Inland Empire Liver Foundation Rialto, California, United States, 92377 United States, Florida Prestige Clinical Research Center Miami, Florida, United States, 33133 Advanced Gastroenterology Associates, LLC Palm Harbor, Florida, United States, 34684 United States, Maryland Meritus Center for Clinical Research Hagerstown, Maryland, United States, 21742 United States, Minnesota Mayo Clinic Rochester, Minnesota, United States, 55905 United States, North Carolina PMG Research of Charlotte Charlotte, North Carolina, United States, 28210 PMG Research of Charlotte Concord, North Carolina, United States, 28025 Cumberland Research Associates, LLC Fayetteville, North Carolina, United States, 28304 Wake Research Associates, LLC Raleigh, North Carolina, United States, 27612 United States, Tennessee Clinical Research Solutions Jackson, Tennessee, United States, 38305 United States, Texas Houston Endoscopy Research Center Houston, Texas, United States, 77079 Wellness Clinical Research Associates McKinney, Texas, United States, 75071 Advanced Clinical Research Associates Plano, Texas, United States, 75093 Less << |
NCT00844831 | Constipation | PHASE4 | COMPLETED | 2025-05-11 | University of Louisville, Loui... More >>sville, Kentucky, 40202, United States Less << |
NCT01166789 | Irritable Bowel Syndrome | Phase 1 | Completed | - | United States, North Carolina ... More >> UNC Clinical and Translational Research Center Chapel Hill, North Carolina, United States, 27599 Less << |
NCT00953043 | - | Completed | - | - | |
NCT00908076 | Parkinson's Disease | Phase 4 | Completed | - | United States, Florida ... More >> University of South Florida Tampa, Florida, United States, 33606 United States, Texas Baylor College of Medicine PDCMDC Houston, Texas, United States, 77030 Less << |
NCT00908076 | - | Completed | - | - | |
NCT00645801 | Colonoscopy | Phase 4 | Completed | - | United States, Michigan ... More >> Henry Ford Hospital Detroit, Michigan, United States, 48202 Henry Ford Health System Novi, Michigan, United States, 48377 Less << |
NCT00953043 | Healthy | Phase 4 | Completed | - | United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less << |
NCT01170039 | Constipation ... More >>Diabetes Less << | Phase 4 | Completed | - | United States, Georgia ... More >> Atlanta Veterans Administration Hospital Atlanta, Georgia, United States, 30033 The Emory Clinic Atlanta, Georgia, United States, 30322 Less << |
NCT00669461 | Constipation|Parkinson's Disea... More >>se Less << | TERMINATED | 2025-09-10 | University of Arkansas for Med... More >>ical Sciences, Little Rock, Arkansas, 72205, United States Less << | |
NCT01236534 | - | Completed | - | - | |
NCT01839734 | HIV | PHASE2 | COMPLETED | 2025-02-16 | Ruth M. Rothstein CORE Center,... More >> Chicago, Illinois, 60612, United States Less << |
NCT01190020 | Chronic Constipation, Methanog... More >>enesis Less << | Phase 1 | Unknown | - | United States, Iowa ... More >> University of Iowa Hospitals and Clinics Recruiting Iowa City, Iowa, United States, 52242 Less << |
NCT01170039 | - | Completed | - | - | |
NCT03010631 | Healthy Volunteers | Phase 3 | Completed | - | United States, Texas ... More >> ICON San Antonio, Texas, United States, 78209 Less << |
NCT01447849 | Constipation | Phase 2 Phase 3 | Completed | - | United States, Texas ... More >> Texas Tech University Health Sciences Center El Paso, Texas, United States, 79905 Less << |
NCT01085643 | Constipation-predominant Irrit... More >>able Bowel Syndrome Less << | Not Applicable | Completed | - | United States, California ... More >> Cedars-Sinai Medical Center Los Angeles, California, United States, 90048 Less << |
NCT01085643 | - | Completed | - | - | |
NCT02138136 | Constipation - Functional | PHASE3 | COMPLETED | 2017-05-01 | University of South Alabama Wo... More >>men's and Children's Hospital, Mobile, Alabama, 36604, United States|Arizona Children's Center at Maricopa Medical Center, Phoenix, Arizona, 85008, United States|Phoenix Children's Hospital, Phoenix, Arizona, 85016, United States|Northwest Arkansas Pediatric Clinic, Fayetteville, Arkansas, 72703, United States|Arkansas Childrens Hospital Research Institute, Little Rock, Arkansas, 72202, United States|WCCT Global, Costa Mesa, California, 92626, United States|Loma Linda University Health Care, Loma Linda, California, 92350, United States|Children's Hospital Los Angeles, Los Angeles, California, 90027, United States|University of California, San Francisco, San Francisco, California, 94143, United States|MCB Clinical Research, Colorado Springs, Colorado, 80910, United States|Nemours/Alfred I. duPont Hospital for Children, Wilmington, Delaware, 19803, United States|Emmerson Clinical Research, Washington, District of Columbia, 20020, United States|University of Florida, Gainesville, Florida, 32610, United States|Palmetto Professional Research, Hialeah, Florida, 33016, United States|Nemours Children's Clinic, Jacksonville, Florida, 32207, United States|Savin Medical Group Research Center, Miami Lakes, Florida, 33014, United States|Acevedo Clinical Research Associates, Miami, Florida, 33142, United States|Nemours Childrens Clinic, Pensacola, Florida, 32504, United States|Children's Center for Digestive Health Care/GI Care for Kids, Atlanta, Georgia, 30342, United States|Methodist Medical Center, Peoria, Illinois, 61602, United States|PediaResearch, LLC - Newburgh, Newburgh, Indiana, 47630, United States|UnityPoint Health Des Moines/ Blank Children's Clinic, Des Moines, Iowa, 50309, United States|University of Iowa Children's Hospital, Iowa City, Iowa, 52242, United States|Heartland Research Associates, Wichita, Kansas, 67205, United States|University of Louisville Research Foundation Inc. Kosair Charities Pediatric Clinical Research Unit, Louisville, Kentucky, 40202, United States|PediaResearch, LLC - Owensboro, Owensboro, Kentucky, 42301, United States|Willis-Knighton Physician Network, Shreveport, Louisiana, 71101, United States|Virgo-Carter Pediatrics, Silver Spring, Maryland, 20910, United States|Gastrointestinal Associates, PA, Jackson, Mississippi, 39202, United States|University of Mississippi Medical Center, Jackson, Mississippi, 39216, United States|The Children's Mercy Hospital, Kansas City, Missouri, 64145, United States|Pioneer Clinical Research, Bellevue, Nebraska, 68005, United States|Smart Medical Research, Inc., Jackson Heights, New York, 11372, United States|NY Presbyterian Weill Cornell, New York, New York, 10021, United States|Morgan Stanley Children's Hospital of New York Presbyterian, New York, New York, 10032, United States|PriMed Clinical Research, Beavercreek, Ohio, 45431, United States|Nationwide Children's Hospital, Columbus, Ohio, 43205, United States|Toledo Children's Hospital, Toledo, Ohio, 43606, United States|University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, 73104, United States|Cyn3rgy Research, Gresham, Oregon, 97030, United States|Square-1 Clinical Research, Inc., Erie, Pennsylvania, 16506, United States|St. Christopher's Hospital for Children Drexel University, Philadelphia, Pennsylvania, 19134, United States|Children's Hospital of Pittsburgh UPMC, Pittsburgh, Pennsylvania, 15224, United States|AAPRI Clinical Research, Warwick, Rhode Island, 02886, United States|Coastal Pediatric Associates - James Island, Charleston, South Carolina, 29412, United States|Coastal Clinical Research, Charleston, South Carolina, 29414, United States|Greenville Health System, Greenville, South Carolina, 29615, United States|Coastal Pediatrics Associates - Mount Pleasant, Mount Pleasant, South Carolina, 29464, United States|Spartanburg Medical Research, Spartanburg, South Carolina, 29303, United States|The Jackson Clinic, P.C., Jackson, Tennessee, 38305, United States|3rd Coast Research Associates, Corpus Christi, Texas, 78413, United States|Childrens Medical Center Dallas, Dallas, Texas, 75390, United States|Cook Children's Medical Center, Fort Worth, Texas, 76104, United States|Baylor College of Medicine, Houston, Texas, 77030, United States|Envision Clinical Research, LLC, Laredo, Texas, 78041, United States|DCOL Center for Clinical Research, Longview, Texas, 75605, United States|Bridgerland Clinical Research, Logan, Utah, 84341, United States|Primary Children's Medical Center, Salt Lake City, Utah, 84132, United States|Wee Care Pediatrics, Syracuse, Utah, 84075, United States|University of Vermont Medical Center, Burlington, Vermont, 05445, United States|Pediatric Research of Charlottesville, LLC, Charlottesville, Virginia, 22902, United States|INOVA Pediatric Digestive Diseases Center, Fairfax, Virginia, 22031, United States|Pediatric Gastroenterology Carilion Medical Center, Roanoke, Virginia, 24014, United States|Northwest Clinicial Research Center, Bellevue, Washington, 98007, United States|Zain Research LLC, Richland, Washington, 99352, United States|MultiCare Health System Institute for Research and Innovation, Tacoma, Washington, 98405, United States|Medical College of Wisconsin, Milwaukee, Wisconsin, 53226, United States|Universitair Kinderziekenhuis Brussel, Brussel, 01090, Belgium|CHC - Clinique Saint-Joseph, Montegnee, 04420, Belgium|Sainte Justine University Health Center, Montreal, H3T1C5, Canada|CHU-Bordeaux, Bordeaux, 33000, France|Emma Children's Hospital, Amsterdam, 1105 AZ, Netherlands|Amphia Ziekenhuis, Breda, 4800 RK, Netherlands|Maasstad Hospital Rotterdam, Rotterdam, 3079 DZ, Netherlands|Isala Klinieken, Zwolle, 8025 AB, Netherlands|Medical University of Bialystok, Bialystok, 15-274, Poland|Szpital Uniwersytecki, Bydgoszcz, 85-168, Poland|Szpital Pediatryczny ICZMP, Lodz, 93-338, Poland|Gabinet Lekarski Bartosc Korczowski, Rzeszow, 35-210, Poland|Przychodnia Specjalistyczna PROSEN, Warszawa, 01-231, Poland|Children's Memorial Health Institute, Warszaw, 04-730, Poland|Darlington Memorial Hospital, Darlington, DL3 6HZ, United Kingdom|Royal London Hospital, London, E1 1BB, United Kingdom|Chelsea and Westminster Hospital NHS Foundation Trust, London, SW10 9NH, United Kingdom|Sheffield Children Hospital, Sheffield, S10 2TH, United Kingdom Less << |
NCT01447849 | - | Completed | - | - | |
NCT02651155 | - | Completed | - | - | |
NCT01469819 | Chronic Idiopathic Constipatio... More >>n Less << | PHASE2|PHASE3 | COMPLETED | 2025-02-15 | Texas Tech University Health S... More >>ciences Center, El Paso, Texas, 79905, United States Less << |
NCT01236534 | Multiple Sclerosis ... More >> Constipation Less << | Phase 4 | Completed | - | United States, New York ... More >> University of Rochester Rochester, New York, United States, 14642 Less << |
NCT01469819 | Chronic Idiopathic Constipatio... More >>n Less << | PHASE2|PHASE3 | COMPLETED | 2025-02-15 | Texas Tech University Health S... More >>ciences Center, El Paso, Texas, 79905, United States Less << |
NCT01324284 | Colorectal Carcinoma | PHASE3 | COMPLETED | 2025-06-11 | - |
NCT03097861 | Chronic Idiopathic Constipatio... More >>n Less << | Phase 3 | Completed | - | - |
NCT02695719 | Constipation | Phase 3 | Completed | - | Korea, Republic of ... More >> Cheonan-si, Chungcheongnam-do, Korea, Republic of Seongnam-si, Gyeonggi-do, Korea, Republic of Iksan-si, Jeollabuk-do, Korea, Republic of Daejeon, Korea, Republic of Seoul, Korea, Republic of Less << |
NCT02651155 | Constipation | Phase 3 | Completed | - | Russian Federation ... More >> Saint-Petersburg, Pushkin, Russian Federation Barnaul, Russian Federation Kazan, Russian Federation Kemerovo, Russian Federation Krasnodar, Russian Federation Moscow, Russian Federation Novosibirsk, Russian Federation Omsk, Russian Federation Saint Petersburg, Russian Federation Saint-Petersburg, Russian Federation Samara, Russian Federation Ulyanovsk, Russian Federation Yaroslavl, Russian Federation Less << |
NCT02729909 | Constipation | Phase 3 | Completed | - | Mexico ... More >> Mexicali, Baja California Norte, Mexico Mexico, Distrito Federal, Mexico Cuautitlan Izcalli, Estado de Mexico, Mexico Tlalnepantla, Estado de Mexico, Mexico Leon, Guanajuato, Mexico Morelia, Michoacan, Mexico Monterrey, Nuevo Le0n, Mexico Culiacan, Sinaloa, Mexico Chihuahua, Mexico Durango, Mexico Less << |
NCT02766777 | Constipation - Functional | PHASE3 | COMPLETED | 2016-11-04 | Northwest Arkansas Pediatric C... More >>linic, Fayetteville, Arkansas, 72703, United States|Methodist Medical Center, Peoria, Illinois, 61602, United States|Willis-Knighton Physician Network, Shreveport, Louisiana, 71101, United States|Pioneer Clinical Research, Bellevue, Nebraska, 68005, United States|PriMed Clinical Research, Beavercreek, Ohio, 45431, United States|Cyn3rgy Research, Gresham, Oregon, 97030, United States|Coastal Clinical Research, Charleston, South Carolina, 29414, United States|Coastal Pediatrics Associates - Mount Pleasant, Mount Pleasant, South Carolina, 29464, United States|Spartanburg Medical Research, Spartanburg, South Carolina, 29303, United States|3rd Coast Research Associates, Corpus Christi, Texas, 78413, United States|Bridgerland Clinical Research, Logan, Utah, 84341, United States|Wee Care Pediatrics, Syracuse, Utah, 84075, United States|Pediatric Research of Charlottesville, LLC, Charlottesville, Virginia, 22902, United States Less << |
Bio Calculators | ||||
Preparing Stock Solutions | ![]() |
1mg | 5mg | 10mg |
1 mM 5 mM 10 mM |
2.56mL 0.51mL 0.26mL |
12.81mL 2.56mL 1.28mL |
25.61mL 5.12mL 2.56mL |
|
Dissolving Methods |
in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day; The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound. Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:
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