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Chemical Structure| 1369452-53-8 Chemical Structure| 1369452-53-8

Structure of KL-11743
CAS No.: 1369452-53-8

Chemical Structure| 1369452-53-8

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KL-11743 is an orally active, glucose-competitive, Class I GLUT inhibitor with IC50 values of 115 nM, 137 nM, 90 nM, and 68 nM for GLUT1, GLUT2, GLUT3, and GLUT4, respectively. It specifically blocks glucose metabolism and can synergize with electron transport inhibitors to induce cell death. Additionally, KL-11743 can induce disulfide bond formation in actin cytoskeletal proteins, leading to disulfidptosis. KL-11743 can be used in cancer research.

Synonyms: KL-11743

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Product Details of KL-11743

CAS No. :1369452-53-8
Formula : C30H30N6O3
M.W : 522.60
SMILES Code : O=C(NC(C)C)COC1=CC=CC(C2=NC(NC3=CC=C(C4=CNN=C4)C=C3)=C5C=C(OCC)C=CC5=N2)=C1
Synonyms :
KL-11743
MDL No. :N/A

Safety of KL-11743

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

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Preparing Stock Solutions 1mg 5mg 10mg

1 mM

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10 mM

1.91mL

0.38mL

0.19mL

9.57mL

1.91mL

0.96mL

19.14mL

3.83mL

1.91mL

 

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