Home Cart Sign in  
Chemical Structure| 1370448-25-1 Chemical Structure| 1370448-25-1

Structure of PF-05221304
CAS No.: 1370448-25-1

Chemical Structure| 1370448-25-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

PF-05221304 is an orally bioavailable, hepato-targeted inhibitor of acetyl-CoA carboxylase (ACC), an enzyme that catalyzes the first step of adipogenesis (DNL).

Synonyms: NSC 170984; R 6238; STAT5 Inhibitor III

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of PF-05221304

CAS No. :1370448-25-1
Formula : C28H30N4O5
M.W : 502.56
SMILES Code : O=C(C1=CC=C(C2=NC(OC)=CC(C(N3CCC4(CC3)CC(C5=C(C4)C=NN5C(C)C)=O)=O)=C2)C=C1)O
Synonyms :
NSC 170984; R 6238; STAT5 Inhibitor III
MDL No. :MFCD33023235
InChI Key :LXZMHBHEXAELHH-UHFFFAOYSA-N
Pubchem ID :57496611

Safety of PF-05221304

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Related Pathways of PF-05221304

ferroptosis

Isoform Comparison

Biological Activity

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT03309202 Hepatic Impairment PHASE1 COMPLETED 2018-07-18 Orlando Clinical Research Cent... More >>er, Orlando, Florida, 32809, United States|Pfizer Clinical Research Unit, Brussels, B-1070, Belgium|Pharmaceutical Research Associates CZ, s.r.o., Praha 7, 170 00, Czechia|Nemocnice Na Bulovce, Praha 8, 180 81, Czechia|Summit Clinical Research s.r.o., Bratislava, 83101, Slovakia|Univerzitná Nemocnica Bratislava, Bratislava, 83305, Slovakia Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.99mL

0.40mL

0.20mL

9.95mL

1.99mL

0.99mL

19.90mL

3.98mL

1.99mL

 

Historical Records

Categories